Collecting health information and samples from people with heart and aorta conditions
Builds a sample bank from people with heart and aorta disease and healthy controls.
Key facts
- Who runs it
- University of Michigan
- Where
- Ann Arbor, United StatesSee the site
- Trial code
- Registry title
- Cardiovascular Health Improvement Project
- Status
- Recruiting
- People taking part
- 15,000 people, planned
- Started
- Aug 2013
- Expected to end
- Aug 2053
- Type of study
- Observational, 2 groups
- Record updated
- 29 April 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people with heart or aorta disease, or a family history of it, and also healthy people with no heart disease. It collects samples for a biobank.
- Age
- Adults over 18, and younger people with parental consent and their own assent if it applies for their age.
- Sex
- All sexes can join.
- Disease stage
- Aortic disease possibly due to an inherited condition, aortic aneurysm of unknown cause, a new kind of aortic or main branch vessel disease, a family history of aortic or vascular disease, or other heart disease. Healthy controls with no apparent heart disease can also join.
Main reasons for not taking part
- People who are not willing or able to sign the consent
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Any patient over the age of 18 who is able/willing to give informed consent
- Patients <18 years of age with parental consent and assent (if assent is applicable for their age)
- Diagnosis of:
- aortic pathology potentially due to a known or suspected inherited condition
- Idiopathic aortic aneurysm
- Interesting of novel vascular pathology in the aorta or main branches
- Family history of aortic or vascular disease
- Other cardiovascular disease
- Healthy controls with no apparent cardiovascular disease
Who cannot take part
- Not willing or able to sign the consent
Where in United States
- University of MichiganAnn Arbor, United StatesContact: Lauren Humphrey-Stark, BSTaking people
About the trial
What the trial wants to find out
The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.
The 2 groups in the trial
- Aortic Disease
Patients with a diagnosis of any form of Aortic Disease
- Controls
Patients without a diagnosis of Aortic Disease
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Cardiovascular Health Improvement Project
- Plain-language title
- Collecting health information and samples from people with heart and aorta conditionsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 29 April 2026