Non-endoscopic EC Screening Program in Northern Iran
Reason given: Waiting to receive capsule sponge device from the manufacturer.
Trial details
- Who runs it
- Tehran University of Medical Sciences
- Trial code
- NCT02311712
- Record updated
- 16 October 2026
- Original description
The aim of this study is to assess the effects of implementation of a non-endoscopic esophageal cancer-screening program on outcomes of interest in an asymptomatic high-risk population in Golestan Province, Iran. Study population will be recruited in two arms. In the intervention arm, cytological examination of the esophagus will be performed using a capsule sponge device. Subjects in the control arm will receive no intervention. All participants will be followed for 5 years. The outcomes of interest, including the incidence of esophageal cancer as well as mortality rates, will be compared between the two groups.Read full original descriptionShow less
Non-endoscopic Esophageal Cancer Screening Program in Northern Iran
The aim of this study is to assess the effects of implementation of a non-endoscopic esophageal cancer-screening program on outcomes of interest in an asymptomatic high-risk population in Golestan Province, Iran. Study population will be recruited in two arms. In the intervention arm, cytological examination of the esophagus will be performed using a capsule sponge device. Subjects in the control arm will receive no intervention. All participants will be followed for 5 years. The outcomes of interest, including the incidence of esophageal cancer as well as mortality rates, will be compared between the two groups.
Inclusion: Participants of Golestan Cohort study with age higher than 50 years.
Exclusion: Subjects with a history of malignant disease, liver cirrhosis, or chronic renal failure will be excluded.