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TerminatedNo phase
Swiss Prospective Autologous Bone Flap Resorption Study
Key facts
- Who runs it
- University of Zurich
- Where
- Switzerland2 sites in 1 countryChoose a country to see its sites
- Trial code
- Status
- Terminated
- People taking part
- 88 people enrolled
- Started
- Jan 2015
- Ended
- 31 Dec 2023
- Type of study
- Observational
- Treatments tested
- Reimplantation of cryoconserved bone flap
- Record updated
- 14 May 2024
- Why it stopped
- Interim analysis confirmed too high rate of bone flap resorption. Continuation of the study was deemed unethical. Available data allow evaluation with sufficient power.
Who can take part
- Age
- 18 years to 99 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- all patients after hemicraniectomy or bifrontal craniectomy
- age 18-99 y/o
- ability to understand and sign informed consent (alternatively, legal representative may sign)
Who cannot take part
- bone flap not fit for reimplantation
- no cryoconservation performed but other technique
- pregnancy
- patient's death
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The complications after reimplantation of cryoconserved autologous bone flaps are reported inhomogeniously in the literature. Especially the incidence of bone flap resorption varies from 0% to about 30%. More recent retrospective studies seem to find higher resorption rates and thus suggest to implant artificial bone replacements from the start. The Swiss Prospective Autologous bone Resorption Study is the first propspective observational study designed to determine the true incidence of autologous bone resorption.
The group in the trial
- Reimplantation of cryoconserved bone flap
All patients who receive reimplantation of a cryoconserved autologous bone flap
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Record updated
- 14 May 2024