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Uses brain MRI scans to find early changes linked to diabetes and memory

Uses brain MRI scans to look for early changes in adults with diabetes.

Plain-language title generated from the registry record
Registry title: The Early Warning System for the Diabetic Encephalopathy

Key facts

Where
Xi'an, ChinaSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 40 and 65 years old?

Source: NCT02420470, who can take part

Where in China

  • Tangdu HospitalXi'an, ChinaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Tang-Du Hospital
Trial code
NCT02420470
Record updated
13 July 2022
Original description
Diabetes( mainly type II diabetes )lead to the central nervous system (CNS) function impairment, especially the mild cognitive impairment that increased the risk of progression to dementia.The primary objectives are defined according to a hierarchical design: i) to tailor and apply multi-parametric, functional MRI techniques to identify cerebral abnormalities (cerebral biomarkers) in type 2 diabetes mellitus and prodromal diabetes mellitus ; ii) to assess whether these cerebral biomarkers are associated with cognitive decrements;iii) to follow up with the putative prediabetic condition patients to verify whether they can transform into diabetes.Read full original descriptionShow less

The Early Warning System for the Central Nervous System Micro-structure Alterations During Early Diabetes Based on the Multi-mode MRIs

Diabetes( mainly type II diabetes )lead to the central nervous system (CNS) function impairment, especially the mild cognitive impairment that increased the risk of progression to dementia.The primary objectives are defined according to a hierarchical design: i) to tailor and apply multi-parametric, functional MRI techniques to identify cerebral abnormalities (cerebral biomarkers) in type 2 diabetes mellitus and prodromal diabetes mellitus ; ii) to assess whether these cerebral biomarkers are associated with cognitive decrements;iii) to follow up with the putative prediabetic condition patients to verify whether they can transform into diabetes.

Inclusion: without dementia; Inform Consent Form; Education time more than 6 years; blood glucose matches the group standard.

Exclusion: suffer from serious brain disease; Pregnant woman; Magnetic resonance contraindications; lack of compliance; image quality is too poor to deal with.

ClinicalTrials.gov NCT02420470