NCT02556736CompletedPhase 1/2
AGN-151597 (Formerly RST-001) Phase I/II Trial for Advanced Retinitis Pigmentosa
Phase I/IIa, Open-Label, Dose-Escalation Study of Safety and Tolerability of Intravitreal RST-001 in Patients With Advanced Retinitis Pigmentosa (RP)
Source: ClinicalTrials.gov · Last updated 12 Jan 2026
Brief summary (registry, in English)
All participants in phase 1 and phase 2a had hand motion visual acuity or worse. If efficacy was demonstrated from phase 1, better vision subjects could be enrolled; however, efficacy was not demonstrated.
- Status (registry)
- Completed
- Phase (registry)
- Phase 1/2
- Study type
- Interventional
- Enrollment
- 14 (actual)
- First submitted
- 21 Sept 2015
- Start date
- 14 Dec 2015
- Primary completion date
- 1 Jun 2020
- Lead sponsor
- AbbVie
- Diseases
- Retinitis pigmentosa
- NCT number
- NCT02556736
What you commit to
- Study type: Interventional · Phase 1/2
- Participants enrolled: 14
- From 14 Dec 2015 to the primary completion date, 1 Jun 2020
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participation in a clinical study (ocular or non-ocular) with an investigational drug, agent or therapy in the past six months.
Other
- Any one of the following will exclude patients from being enrolled into the study:
- Unable or unwilling to meet requirements of the study.
Who the study is looking for
- Participants must meet all of the following criteria.
- Age \>= 18 years.
- Signed and dated written informed consent obtained from the patient.
- Ability to comply with testing and all protocol tests.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Retina Foundation of the Southwest /ID# 235199 Coordinator of this site? Confirm its status | Dallas | United States | Unknown status |
| Duke Eye Center /ID# 235715 Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
| Cincinnati Eye Institute- Edgewood /ID# 236713 Coordinator of this site? Confirm its status | Edgewood | United States | Unknown status |
| University of California San Francisco - Mission Bay /ID# 235717 Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.