Developing a Risk Score to Spot Dangerous Heart Artery Plaques
Studies coronary CT scans with clinical factors to find people at risk of heart attack.
Plain-language title generated from the registry record
Registry title: National Plaque Registry and Database
Key facts
- Where
- Budapest, Debrecen, Eger, Győr, Gyula, Kaposvár, Miskolc, Pécs, Szeged, and Szombathely, HungarySee the 11 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 90 years old?
Source: NCT02578355, who can take part
Where in Hungary
- Homeland Defence HospitalBudapest, HungaryNo longer taking part
- Pozitron Diagnostic CenterBudapest, HungaryNo longer taking part
- University of DebrecenDebrecen, HungaryNo longer taking part
- Markhot Ferenc Teaching Hospital and ClinicEger, HungaryNo longer taking part
- Petz Aladar County Teaching HospitalGyőr, HungaryNo longer taking part
- Pándy Kálmán County HospitalGyula, HungaryNo longer taking part
- Health Centrum, Kaposvár UniversityKaposvár, HungaryNo longer taking part
- Borsod-Abaúj-Zemplén County Hospital and Teaching HospitalMiskolc, HungaryNo longer taking part
- University of PecsPécs, HungaryNo longer taking part
- University of SzegedSzeged, HungaryNo longer taking part
- Markusovszky Teaching HospitalSzombathely, HungaryNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Semmelweis University Heart and Vascular Center
- Trial code
- NCT02578355
- Record updated
- 25 April 2017
- Original description
The ultimate goal of this project is to develop a risk score to identify patients with vulnerable coronary atherosclerotic plaques, who are prone to suffer acute coronary syndrome. Early identification of vulnerable plaques may have an enormous impact on public health through primary and secondary prevention of acute myocardial infarction.Read full original descriptionShow less
National Plaque Registry and Database
The ultimate goal of this project is to develop a risk score to identify patients with vulnerable coronary atherosclerotic plaques, who are prone to suffer acute coronary syndrome. Early identification of vulnerable plaques may have an enormous impact on public health through primary and secondary prevention of acute myocardial infarction.
Investigators hypothesize that a risk score that incorporates non-invasive coronary CT imaging (calcium score and/or coronary CTA) in combination with clinical characteristics (classical risk prediction models) will improve the identification of patients who are at highest risk to suffer myocardial infarction or sudden cardiac death.
The overall goal of the OPeRA project is to develop, implement and validate a novel risk assessment tool based on image markers and clinical characteristics to identify patients who are at increased risk to suffer myocardial infarction or sudden cardiac death.
Inclusion: Age > 18 years; Subject providing written informed consent; Scheduled to undergo a clinically indicated coronary CTA.
Exclusion: Recent prior myocardial infarction within 30 days prior to coronary CTA or between coronary CTA and ICA; Suspicion of acute coronary syndrome (acute myocardial infarction and unstable angina); Evidence of ongoing or active clinical instability, including acute chest pain (sudden onset), cardiogenic shock, unstable blood pressure with systolic blood pressure <90 mmHg, and severe congestive heart failure (NYHA III or IV) or acute pulmonary edema; Age <18 years; Pregnancy or unknown pregnancy status in subject of childbearing potential; Subject requires an emergent procedure; Inability to comply with study procedures.