Studies inherited genes that may raise the risk of thyroid cancer
Collects family history and a sample from people with thyroid cancer.
Plain-language title generated from the registry record
Registry title: Hereditary Risk Factors for Thyroid Cancer
Key facts
- Where
- Boston, United StatesSee the site
Where in United States
- Dana-Farber Cancer InstituteBoston, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Dana-Farber Cancer Institute
- Trial code
- NCT02747888
- Record updated
- 11 June 2026
- Original description
Thyroid cancers can occur sporadically, but can also be found as tumors that cluster in families with other cancers or genetic syndromes. Researchers are studying thyroid cancer in children and families, with a particular interest in understanding genes and other factors that may put individuals at risk for developing thyroid cancer and thyroid nodules.Read full original descriptionShow less
Hereditary Risk Factors for Thyroid Cancer
Thyroid cancers can occur sporadically, but can also be found as tumors that cluster in families with other cancers or genetic syndromes. Researchers are studying thyroid cancer in children and families, with a particular interest in understanding genes and other factors that may put individuals at risk for developing thyroid cancer and thyroid nodules.
* In this study, family and medical history information is collected alongside a blood or saliva sample for genetic studies. * Individuals with a past or present childhood thyroid cancer/nodule or a thyroid cancer suspected to be inherited in their family are invited to participate.
Inclusion: Individual pediatric patient with current or previous known or suspected thyroid cancer or nodule(s); Individual adult patient with current or previous known or suspected thyroid cancer or nodule(s) if they come from a family with a high suspicion of hereditary cancer (as below); Individuals from families with a high suspicion of hereditary thyroid cancer:; Families with a current or previous diagnosis of a thyroid cancer/nodule occurring in childhood (<18 years old); Families with a high suspicion of hereditary thyroid cancer/nodules other than above to include:; Families with thyroid cancer in multiple individuals; Families with thyroid cancer and a known genetic syndrome; Families with thyroid cancer and a suspected genetic syndrome (e.g. multiple childhood cancers in the family, multiple primary cancers, multiple endocrinopathies, etc.).
Exclusion: Individuals who are unable to give informed consent; Individuals who are unable to complete study materials.