Monitors people with HIV after a treatment pause in earlier studies
Follows adults with HIV who first started treatment during early infection and paused it.
Plain-language title generated from the registry record
Registry title: Post Analytic Treatment Interruption Study
Key facts
- Where
- Bangkok, ThailandSee the site
Where in Thailand
- SEARCHBangkok, ThailandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- SEARCH Research Foundation
- Trial code
- NCT02761200
- Record updated
- 27 April 2026
- Original description
This exploratory study is designed to ensure the safety of HIV-infected volunteers who complete research protocols that include an analytic treatment interruption (ATI). This is a prospective cohort study of volunteers who were diagnosed with HIV during early acute HIV infection, treated with antiretroviral therapy (ART) and subsequently enrolled in a clinical study that included ATI. After completion of study participation that involves ATI, participants will be recruited into this study for continued clinical and laboratory monitoring.Read full original descriptionShow less
Safety and Virologic Outcomes After HIV Remission Trials in Patients Who Initiated Antiretroviral Therapy During Early Acute HIV Infection
This exploratory study is designed to ensure the safety of HIV-infected volunteers who complete research protocols that include an analytic treatment interruption (ATI). This is a prospective cohort study of volunteers who were diagnosed with HIV during early acute HIV infection, treated with antiretroviral therapy (ART) and subsequently enrolled in a clinical study that included ATI. After completion of study participation that involves ATI, participants will be recruited into this study for continued clinical and laboratory monitoring.
Inclusion: Man or woman aged ≥18 years; Enrolled in RV254 study; Completed clinical research protocol that included ATI within one month of enrollment in this protocol; Able and willing to provide written informed consent or, in the case of illiteracy, witnessed verbal informed consent with documentation of a thumbprint in lieu of a signature; Able to participate in study visits for up to 144 weeks; Willing to have photo or fingerprint taken for identification purposes; Female-specific criteria: Agrees not to become pregnant while not receiving ART. If a woman is sexually active and has no history of hysterectomy or tubal ligation or menopause, she must agree to engage in abstinence, use a prescription birth control method or use a barrier birth control method while not receiving ART.
Exclusion: History of a medical or psychiatric condition that, in the opinion of investigator, would jeopardize the safety or rights of the subject, such as a condition that would interfere with or serve as a contraindication to adherence to the study protocol or ability to give informed consent.