Calorie-Restricted Diet Tested Before Surgery For Sarcoma Patients
Tests a reduced-calorie diet in adults with sarcoma receiving radiation before surgery.
Plain-language title generated from the registry record
Registry title: Caloric Restriction In Sarcoma Patients Treated With Pre-Operative RT
Key facts
- Where
- Boston, United StatesSee the site
Where in United States
- Massachusetts General HospitalBoston, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Massachusetts General Hospital
- Trial code
- NCT02792270
- Record updated
- 9 October 2026
- Original description
This study is being conducted to decrease the rate of surgical wound complications. The investigators are studying the effects that caloric restriction has on decreasing the rate of surgical wound complications.Read full original descriptionShow less
Effects Of Caloric Restriction On Post-Operative Complications In Sarcoma Patients Treated With Pre-Operative Radiation Therapy
This study is being conducted to decrease the rate of surgical wound complications. The investigators are studying the effects that caloric restriction has on decreasing the rate of surgical wound complications.
Inclusion: Age >18 years; Biopsy proven soft tissue sarcoma located in the lower extremities; Patient to be treated with radiation therapy for a primary lower extremity soft tissue sarcoma or recurrent tumor after surgery, followed by surgical resection; Karnofsky Score ≥ 60%; Body Mass Index (BMI) ≥ 20 kg/m2; Protein levels within normal limits within 45 days of enrollment; Normal kidney and liver function within 45 days of enrollment; Normal blood counts within 45 days of enrollment; Normal chemistries within 45 days of enrollment.
Exclusion: Current metformin therapy; Other cancers diagnosed within the last 5 years (in situ and/or invasive); Diabetes mellitus; Other conditions may exclude participants from the study (e.g. intractable nausea/emesis, allergic reaction to shake, patient decides not to have surgery, any medical condition that prevents patient from having surgery); Current pregnancy and breast feeding.