NCT02795052Recruiting
Neurologic Stem Cell Treatment Study
Neurologic Bone Marrow Derived Stem Cell Treatment Study
Source: ClinicalTrials.gov · Last updated 26 Jun 2026
Brief summary (registry, in English)
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will provide improvement in neurologic function for patients with certain neurologic conditions. http://mdstemcells.com/nest/
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 500 (estimated)
- First submitted
- 6 Jun 2016
- Start date
- Jun 2016
- Primary completion date
- 31 Jul 2027
- Lead sponsor
- MD Stem Cells
- Diseases
- ALS (motor neurone disease), Frontotemporal dementia, Lewy body dementia, Stroke, Alzheimer disease, Parkinson disease, Multiple sclerosis
- NCT number
- NCT02795052
What you commit to
- Study type: Interventional
- Planned participants: 500
- From Jun 2016 to the primary completion date, 31 Jul 2027
- 3 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Women of childbearing age must not be pregnant at the time of treatment and should refrain from becoming pregnant for 3 months post treatment.
Other
- All patients must be capable of an adequate neurologic examination and evaluation to document the pathology. This will include the ability to cooperate with the exam.
- Patients must be capable and willing to undergo follow up neurologic exams with the sub-investigators or their own neurologists as outlined in the protocol.
- Patients must be capable of providing informed consent.
- In the estimation of Dr. Weiss the BMSC collection and treatment will not present a significant risk of harm to the patient's general health or to their neurologic function. .
- Patients who are not medically stable or who may be at significant risk to their health undergoing the procedure will not be eligible.
Who the study is looking for
- Have documented functional damage to the central or peripheral nervous system unlikely to improve with present standard of care.
- Be at least 6 months post-onset of the disease.
- If under current medical therapy (pharmacologic or surgical treatment) for the condition be considered stable on that treatment and unlikely to have reversal of the associated neurologic functional damage as a result of the ongoing pharmacologic or surgical treatment.
- In the estimation of Dr. Weiss and the neurologists have the potential for improvement with BMSC treatment and be at minimal risk of any potential harm from the procedure.
- Be over the age of 18 and capable of providing informed consent.
- Be medically stable and able to be medically cleared by their primary care physician or a licensed primary care practitioner for the procedure. Medical clearance means that in the estimation of the primary care practitioner, the patient can reasonably be expected to undergo the procedure without significant medical risk to health.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Saudi-German Hospital Coordinator of this site? Confirm its status | Dubai | United Arab Emirates | Recruiting |
| MD Stem Cells Coordinator of this site? Confirm its status | Coral Springs | United States | Recruiting |
| MD Stem Cells Coordinator of this site? Confirm its status | Westport | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.