Studying slowed movement and brain changes in people with Alzheimer's disease
Looks at brain scans and tests of thinking in adults with Alzheimer's disease.
Plain-language title generated from the registry record
Registry title: Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease
Key facts
- Where
- Amiens, FranceSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with mild memory problems or mild dementia (Alzheimer's, Lewy body or frontotemporal), seen at the Amiens memory centre, and healthy volunteers.
- Age
- 40 to 85 years
- Sex
- All sexes can join.
- Disease stage
- Mild cognitive impairment, or mild dementia (MMSE above 20) due to Alzheimer's disease, Lewy body disease or frontotemporal lobar degeneration.
- Earlier treatment
- People on psychotropic medicines cannot join, except for anxiolytics or antidepressants stopped or started in the previous month.
Main reasons for not taking part
- Reading or writing difficulties from a learning disorder or illiteracy
- Other past or present brain or nerve disorders, such as stroke, meningitis, severe head injury or epilepsy needing treatment
- Heart, lung, liver or kidney problems that could affect thinking, or alcohol abuse
- Pregnancy
- Cannot have a brain MRI or a neuropsychological evaluation
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 85 years old?
Source: NCT02811653, who can take part
Where in France
- CHU AmiensAmiens, FranceContact: Daniela ANDRIUTA, PhDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Centre Hospitalier Universitaire, Amiens
- Trial code
- NCT02811653
- Record updated
- 28 May 2026
- Original description
In AD (Alzheimer disease), the anatomic correlates of attention disorders (as evaluated by motor slowing) have not been thoroughly characterized.Read full original descriptionShow less
Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease
In AD (Alzheimer disease), the anatomic correlates of attention disorders (as evaluated by motor slowing) have not been thoroughly characterized.
Inclusion: Patients; Age between 40 and 85; French mother tongue; Consulting at the Amiens Memory Resource and Research Centre (CMRR) for:; MCI, according to Albert et al.'s criteria (Albert et al., 2011); Mild dementia (MMSE>20) due to AD, according to McKhann's criteria (McKhann et al., 2011); Mild dementia due to LBD, according to McKeith et al.'s criteria (McKeith et al., 2005); Mild dementia due to FTLD, according to Rascovsky et al.'s criteria (Rascovsky et al., 2011); Social security coverage; Healthy controls; Healthy age and gender matched volunteers will be recruited into the study from the general population.
Exclusion: Past or present neurological disorders other than those having prompted consultation in the Memory Clinic:; stroke; meningitis or encephalitis; severe head injury; sensorimotor impairments (sensory, proprioceptive, cerebellar and visual impairments); epilepsy (requiring ongoing treatment),; psychiatric disorders (other than treated depression); treatment with psychotropic medications (other than anxiolytics or antidepressant withdrawn or initiated in the previous month). Patients with parkinsonian syndrome were examined in the "on-drug" state; Contra-indication to MRI:; nerve stimulators; cochlear implants; ferromagnetic foreign bodies close to nervous structures in the eye or brain; cerebral shunts; dental appliances; Reading or writing difficulties related to a learning disorder or illiteracy; A medical history with a potentially significant impact on cognition (non-corrected thyroid disorders or heart failure):; NYHA stage IV dyspnoea; respiratory impairment requiring oxygen therapy; liver impairment; kidney failure, progressing neoplastic disease, or past or present alcohol abuse; Impossibility to perform a neuropsychological evaluation or brain MRI; Withdrawal from the study at any time, if desired; Pregnancy; Legal guardianship or incarceration.