Studies growth signaling in cells from the human heart
Examines growth-factor signaling in heart cells from people with heart disease.
Plain-language title generated from the registry record
Registry title: Studies of Neuregulin/ERBB Signaling in Human Heart
Key facts
- Where
- Portland, United StatesSee the site
Where in United States
- Maine Medical CenterPortland, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Douglas B. Sawyer
- Trial code
- NCT02820233
- Record updated
- 3 April 2025
- Original description
This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.Read full original descriptionShow less
Isolation and Characterization of ERBB Expressing Human Heart Progenitor Cells
This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.
Inclusion: Clinical diagnosis of severe coronary artery disease scheduled to undergo coronary artery bypass surgery.
Exclusion: constrictive pericarditis or other significant pericardial disease; severe pulmonary hypertension; severe ventricular arrhythmias; significant renal impairment (Cr > 2.5 mg/dL); less than 18 years of age; unwilling or unable to provide informed consent; known active myocarditis; hypertrophic cardiomyopathy; pregnancy.