Compares two dialysis salt levels in people with kidney failure
Tests two dialysis sodium levels in adults receiving maintenance haemodialysis for kidney failure.
Plain-language title generated from the registry record
Registry title: Randomised Evaluation of Sodium Dialysate Levels on Vascular Events
Key facts
- Where
- Adelaide, Auburn, Bedford Park, Bentleigh East, Birtinya, Brisbane, Bundaberg, Caloundra, Camperdown, Canberra, Frankston, Gympie, Ipswich, Mackay, Meadowbrook, Melbourne, Nambour, Northfield, Pialba, St Leonards, Sunshine Coast, Sydney, and Woodville South, AustraliaSee the 31 sites
- Phase
- Phase 4
Where in Australia
- Royal Adelaide HospitalAdelaide, AustraliaTaking people
- Auburn HospitalAuburn, AustraliaTaking people
- Flinders Medical CentreBedford Park, AustraliaTaking people
- Moorabbin HospitalBentleigh East, AustraliaTaking people
- Sunshine Coast University Private HospitalBirtinya, AustraliaTaking people
- Princess Alexandra HospitalBrisbane, AustraliaTaking people
- Redlands HospitalBrisbane, AustraliaTaking people
- Bundaberg HospitalBundaberg, AustraliaTaking people
- Caloundra HospitalCaloundra, AustraliaTaking people
- Royal Prince Alfred HospitalCamperdown, AustraliaTaking people
- The Canberra HospitalCanberra, AustraliaTaking people
- Peninsula HealthFrankston, AustraliaTaking people
- Gympie HospitalGympie, AustraliaTaking people
- Ipswich HospitalIpswich, AustraliaTaking people
- Mackay Base HospitalMackay, AustraliaTaking people
- Logan HospitalMeadowbrook, AustraliaTaking people
- Casey HospitalMelbourne, AustraliaTaking people
- Cranbourne Integrated Care CentreMelbourne, AustraliaTaking people
- Monash Health Community DandenongMelbourne, AustraliaTaking people
- Nambour General HospitalNambour, AustraliaTaking people
- Hampstead Dialysis CentreNorthfield, AustraliaTaking people
- Hervey Bay HospitalPialba, AustraliaTaking people
- Royal North Shore HospitalSt Leonards, AustraliaTaking people
- Sunshine Coast University HospitalSunshine Coast, AustraliaTaking people
- Blacktown Regional Dialysis CentreSydney, AustraliaTaking people
- Concord Repatriation and General HospitalSydney, AustraliaTaking people
- Mt Druitt Community Dialysis CentreSydney, AustraliaTaking people
- Nepean HospitalSydney, AustraliaTaking people
- Sydney Adventist HospitalSydney, AustraliaTaking people
- Westmead HospitalSydney, AustraliaTaking people
- The Queen Elizabeth HospitalWoodville South, AustraliaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Sydney
- Trial code
- NCT02823821
- Record updated
- 4 April 2025
- Original description
This global study will assess the effect of randomising dialysis sites to one of two default dialysate sodium concentrations in current practice, 140mmol/l and 137mmol/l, on major cardiovascular events and death in patients receiving maintenance haemodialysis.Read full original descriptionShow less
Randomised Evaluation of Sodium Dialysate Levels on Vascular Events
This global study will assess the effect of randomising dialysis sites to one of two default dialysate sodium concentrations in current practice, 140mmol/l and 137mmol/l, on major cardiovascular events and death in patients receiving maintenance haemodialysis.
The site inclusion criteria are:; Predominantly dialyses adults (≥18 years old) receiving maintenance haemodialysis; Rates of withdrawal within the first two years of commencing dialysis for social reasons have been less than 15% for the 2 years prior to recruitment and are not expected to increase above 15%; Has a minimum of 10 dialysis recipients at time of randomisation; Utilises a default dialysate sodium concentration at the time of recruitment (a substantial majority of dialysis sessions are conducted with the default dialysate sodium concentration); Is a self-contained unit (i.e. unit patients do not regularly rotate through another unit. Brief trips by patients to a parent or other unit do not exclude a site); Willing to accept randomisation to either intervention (as determined by nominated Director of Unit); Is not a home dialysis training or support unit. [Sites that include both in-center/satellite dialysis patients and home patients may participate but the study procedures and assessments will only be conducted in the incenter/satellite component of the site]; The exclusion criteria are:; Not able to comply with data collection methods.