Taking people in United StatesNo phase

Registry following people with blood clots in the veins

Collects health information on people with venous thromboembolism, including groups often left out of trials.

Key facts

Who runs it: Manuel Monreal
Where: Boston, Evanston, Jacksonville, Manhasset, Milwaukee, and New Haven, United StatesSee the 6 sitesAlso in 28 other countries, 298 sites
Trial code: NCT02832245
Registry title: Computerized Registry of Patients With Venous Thromboembolism (RIETE)
Status: Recruiting
People taking part: 120,000 people, planned
Started: Mar 2001
Expected to end: Dec 2027
Type of study: Observational
Record updated: 21 September 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people with a confirmed blood clot in the veins. Their health and treatment details are collected in a registry.

Sex: All sexes can join.
Disease stage: Venous thromboembolism confirmed by objective tests: acute deep-vein thrombosis, pulmonary embolism (clot in the lung) and/or superficial venous thrombosis.

Main reasons for not taking part

Taking part in a treatment trial with an unknown drug.
Not able to have the 3 month follow-up.

The registry criteria, word for word

Show all 4 criteriaShow less

Who can take part

Confirmed VTE (acute deep-vein thrombosis, pulmonary embolism and/or superficial venous thrombosis) by objective tests
Informed consent to the participation in the study, according to the requirements of the ethics committee within each hospital

Who cannot take part

Participation in a therapeutic clinical trial with an unknown drug
Inability to the 3 month follow-up

Where in United States

Also in 28 other countries, 298 sites

Massachusetts General HospitalBoston, United StatesContact: Gaurav M ParmarTaking people
Evanston NorthShore University HealthSystemEvanston, United StatesContact: Alfonso TafurTaking people
College of Medicine - Jacksonville University of FloridaJacksonville, United StatesContact: Luis Ortega PazTaking people
Northwell Health SystemManhasset, United StatesContact: Mayra HawkinsNo longer taking part
Medical College of WisconsinMilwaukee, United StatesContact: Mayra HawkinsNo longer taking part
Yale University School Of MedicineNew Haven, United StatesContact: Mayra HawkinsNo longer taking part

About the trial

What the trial wants to find out

The Computerized Registry of Patients with Venous Thromboembolism (RIETE) is a multidisciplinary Project initiated in march 2001 and consisting in obtaining an extensive data registry of consecutive patients with venous thromboembolism.

Read full original descriptionShow less

The main objective is to provide information on the Internet to help physicians to improve their knowledge on the natural history of thromboembolic disease, particularly in those subgroups of patients who are usually not recruited in randomized clinical trials (pregnant women, elderly patients, disseminated cancer, severe renal insufficiency, patients with contraindications to anticoagulation therapy, extreme body weight, etc), with the purpose of decreasing mortality, frequency of thromboembolic recurrences as well as bleeding complications and arterial events.

As an additional objective RIETE is also aimed to create predictive scores that help physicians to better identify patients with high risk of presenting some of these complications.

The primary parameters recorded by the registry comprise details of each patient's clinical status, including any coexisting or underlying conditions, and the type, dose, duration and outcome (during the first 3 months of therapy) of antithrombotic treatment. Study endpoints are clinically recognized (and objectively confirmed) recurrences of VTE, major and minor bleeding complications, and death.