Surgery for bowel endometriosis before IVF in women with infertility
Tests bowel surgery before IVF in women aged 18 to 38 with endometriosis and infertility.
Plain-language title generated from the registry record
Registry title: Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility
Key facts
- Where
- Clermont-Ferrand, Lille, Paris, Poissy, and Rouen, FranceSee the 5 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 38 years old?
Source: NCT02948972, who can take part
Where in France
- CHUClermont-Ferrand, FranceTaking people
- Hôpital Jeanne de Flandres, CHRULille, FranceTaking people
- AP-HP - Hopital TenonParis, FranceTaking people
- CHUPoissy, FranceTaking people
- CHURouen, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Lille
- Trial code
- NCT02948972
- Record updated
- 22 April 2026
- Original description
The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility. Patients will be randomized in two parallel-groups; one group underwent complete surgery of colorectal DIE prior to ART and the other group underwent ART alone (ratio 1:1)Read full original descriptionShow less
Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility: Complete Surgery + IVF Versus IVF (ENDOFERT)
The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility. Patients will be randomized in two parallel-groups; one group underwent complete surgery of colorectal DIE prior to ART and the other group underwent ART alone (ratio 1:1)
Inclusion: Primary and secondary infertility; Indication for IVF; Persistent pain related to endometriosis with analgesic medical treatment failure; Persistent pain including at least one of the following digestive symptoms related to endometriosis: Dyschesia / Sub-occlusive syndrome / Rectal bleeding / Painful defecation; Colorectal deep infiltrating endometriosis : Whatever lesion size / With at least rectal serosal involvement / Confirmed by MRI and 1 different investigation: vaginal ultrasound echography or coloscopic CT scan or rectal endoscope ultrasound; Eligible for DIE surgery.
Exclusion: Previous IVF cycle(s); Previous colorectal surgery; Need of myomectomy during surgery; Contraindication to pregnancy or to IVF; Viral risk; The use of oocytes donor.