Study of Cardiac PET/CT Imaging to Guide Ablation Treatment of Ventricular Tachycardia
Reason given: Investigator departing institution and enrollment not met.
Key facts
- Where
- St Louis, United StatesSee the site
- Phase
- Early phase 1
Where in United States
- Mercy Hospital St. LouisSt Louis, United StatesNo longer taking part
Trial details
- Who runs it
- Khaled Awad, MD
- Trial code
- NCT02962076
- Record updated
- 24 December 2024
- Original description
Imaging is to be performed prior to procedure using positron emission tomography/ computed tomography (PET/CT), after a special dye is injected. The scans are going to be merged with other cardiac scans when doing the ablation procedure to correlate anatomy with physiology.Read full original descriptionShow less
Cardiac Positron Emission Tomography for Detection of Cardiac Sympathetic Dysinnervation to Guide Ablation of Ventricular Tachycardia
Imaging is to be performed prior to procedure using positron emission tomography/ computed tomography (PET/CT), after a special dye is injected. The scans are going to be merged with other cardiac scans when doing the ablation procedure to correlate anatomy with physiology.
Inclusion: Clinical indication for ventricular tachycardia (VT) ablation (at least one clinical episode of sustained VT) despite antiarrhythmic drug therapy, or if the patient does not wish to be on one; Ischemic or nonischemic cardiomyopathy; Sustained monomorphic VT.
Exclusion: General contraindications to VT ablation, e.g., major contraindication to anticoagulation therapy, known presence of left ventricular thrombus, reversible causes of VT or VF; Polymorphic VT or ventricular fibrillation (VF) being the sole detected clinical arrhythmia; Recent myocardial infarction less than 30 days; Right ventricular VT; Patient is unable to sign informed consent; Recent ablation for ventricular tachycardia less than 30 days; Patient is unwilling or unable to cooperate with the study; Prosthetic mitral or aortic valve; General contraindications to PET imaging, e.g., pregnancy or lactation; General contraindication to magnetic resonance imaging or to the administration of gadolinium; Contraindication to the placement of hemodynamic support devices, i.e. the presence of mechanical valves or lack of adequate vascular access.