NCT02966145Completed
4-Repeat Tauopathy Neuroimaging Initiative - Cycle 2
The Four-Repeat Tauopathy Neuroimaging Initiative
Source: ClinicalTrials.gov · Last updated 13 Apr 2025
Brief summary (registry, in English)
The goal of this study is to identify the most reliable methods of analysis for tracking CBD, PSP, and o/vPSP over time. The results from this study may be used in the future to calculate statistical power for clinical drug trials. The study will also provide information about the relative value of novel imaging techniques for diagnosis, as well as the value of imaging techniques versus testing of blood, urine, and cerebrospinal fluid (CSF) 'biomarkers'.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 293 (actual)
- First submitted
- 15 Nov 2016
- Start date
- Jan 2016
- Primary completion date
- 28 Feb 2024
- Lead sponsor
- University of California, San Francisco
- Diseases
- Frontotemporal dementia
- NCT number
- NCT02966145
What you commit to
- Study type: Observational
- Participants enrolled: 293
- From Jan 2016 to the primary completion date, 28 Feb 2024
- 8 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Significant neurological disease other than CBD, PSP, or a variant PSP syndrome.
- Presence of pacemakers, aneurysm clips, artificial heart valves, ear implants, or metal fragments or metal objects in the eyes, skin, or body
- In the site investigator's opinion, inability to complete sufficient key study procedures, or some other equivalent assessment of impairment
Who the study is looking for
- No known history of neurological disease, or meet criteria for one of the following: Corticobasal Syndrome or Degeneration (CBS or CBD); Progressive Supranuclear Palsy (PSP); or Oligo- or Variant- Progressive Supranuclear Palsy (o/vPSP)
- Needs a reliable study partner who has frequent contact with the participant, who is available to provide information about the participant, and who can accompany the participant to research visits as needed
- Must be willing and able to undergo testing procedures, which include longitudinal follow-up visits
- Must be able to walk five steps with minimal assistance
Age in the registry: 40 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Toronto Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
| Johns Hopkins University Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| Harvard University - Massachusetts General Hospital Coordinator of this site? Confirm its status | Charlestown | United States | Unknown status |
| Columbia University Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Mayo Clinic - Rochester Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
| University of California, San Diego (UCSD) Coordinator of this site? Confirm its status | San Diego | United States | Unknown status |
| University of California, San Francisco (UCSF) Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.