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99Tc-MDP Treatment for Knee Osteoarthritis

This trial has no sites in United States.

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Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Trial code
NCT02993029
Record updated
28 April 2026
Original description
Osteoarthritis (OA) of knee is the most common form of arthritis in the world1e, and it has received growing attention in the society because of the increase of old age population, disabled people, and medical expenses from this disease. 99Tc-MDP is effective for rheumatoid arthritis. Therefore, the investigators try to investigate the effects of 99Tc-MDP treatment in patients with osteoarthritis of knee as compared with celecoxib.Read full original descriptionShow less

99Tc-MDP Versus Celecoxib Treatment in Patients With Knee Osteoarthritis

Osteoarthritis (OA) of knee is the most common form of arthritis in the world1e, and it has received growing attention in the society because of the increase of old age population, disabled people, and medical expenses from this disease. 99Tc-MDP is effective for rheumatoid arthritis. Therefore, the investigators try to investigate the effects of 99Tc-MDP treatment in patients with osteoarthritis of knee as compared with celecoxib.

Inclusion: Participants with painful osteoarthritis; The standard uptake value (SUV) of OA related knee greater than 10 on 18F- sodium fluoride bone scan; Participants voluntarily participate in the trial, and signed the informed consent.

Exclusion: Inflammatory arthritis or joint infection of knee; Nervous joint disease; Knee joint replacement; Fracture of joint; Gout arthritis of the knee; Traumatic arthritis.

ClinicalTrials.gov NCT02993029