NCT03004326Recruiting
Clinical Transcriptomics in Systemic Vasculitis (CUTIS)
Source: ClinicalTrials.gov · Last updated 22 Jan 2026
Brief summary (registry, in English)
Multi-center observational study to evaluate the histopathology and transcriptome of cutaneous lesions in patients with several different types of vasculitis.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 20 Dec 2016
- Start date
- 1 Jan 2017
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Peter Merkel
- Diseases
- ANCA-associated vasculitis
- NCT number
- NCT03004326
What you commit to
- Study type: Observational
- Planned participants: 50
- From 1 Jan 2017 to the primary completion date, 31 Dec 2028
- 10 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Considered not to be a candidate for a biopsy or have a higher risk of developing an infection, bleeding, etc., from the biopsy, or a doctor believes that the risks for you participating in this study do not outweigh the potential benefit of learning information from your biopsy
- You have an uncontrolled disease that could prevent you from completing the study procedures
- You have an active infection at or near the potential biopsy site, have poor circulation, or have bony prominence or other structure that would increase your risk of complications if you participated in this study
Lab values
- You have a neutrophil count (type of white blood cell) less than 1500/mm3, platelet count less than 50,000/mm3, or a hemoglobin less than 7 g/dL
Age
- You are less than five years old
Other
- You are pregnant or nursing
- You are not able to provide informed consent
Who the study is looking for
- Have a cutaneous lesion (purpuric macules, palpable purpura, retiform purpura, nodules, ulcers, or urticarial) believed to be related to active vasculitis
- Have a suspected or confirmed diagnosis of:
- Cryoglobulinemic vasculitis (CV)
- Drug-induced vasculitis
- Eosinophilic granulomatosis with polyangiitis (EGPA)
- IgA vasculitis
- Isolated cutaneous vasculitis
- Granulomatosis with polyangiitis (GPA)
- Microscopic polyangiitis (MPA)
- Polyarteritis nodosa (PAN)
- Urticarial vasculitis
- Be willing and able to provide written informed consent (or assent for those under
Age in the registry: 5 years to - · Sex: All · Does not accept healthy volunteers
Sites (10)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| St. Joseph's Healthcare Coordinator of this site? Confirm its status | Hamilton | Canada | Recruiting |
| University of Toronto Mount Sinai Hospital Coordinator of this site? Confirm its status | Toronto | Canada | Recruiting |
| Boston University School of Medicine Coordinator of this site? Confirm its status | Boston | United States | Completed |
| University of Virginia Coordinator of this site? Confirm its status | Charlottesville | United States | Recruiting |
| Cleveland Clinic Coordinator of this site? Confirm its status | Cleveland | United States | Completed |
| University of California, Los Angeles Coordinator of this site? Confirm its status | Los Angeles | United States | Completed |
| University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
| Oregon Health Science University Coordinator of this site? Confirm its status | Portland | United States | Completed |
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Completed |
| University of Utah Coordinator of this site? Confirm its status | Salt Lake City | United States | Completed |
This page is information, not medical advice. Discuss any trial with your doctor.