Active, not recruitingNo phase
A Multicenter Prospective Randomized Control Study on Persona Total Knee System vs NexGen
Key facts
- Who runs it
- Zimmer Biomet
- Where
- Denmark5 sites in 1 countryChoose a country to see its sites
- Trial code
- Status
- Active, not recruiting
- People taking part
- 332 people enrolled
- Started
- Dec 2016
- Expected to end
- 31 Dec 2031
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Persona total knee system
- Nexgen total knee system
- Record updated
- 12 May 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 14 criteriaShow less
Who can take part
- Clinical and radiological osteoarthritis of the knee set to receive a primary unilateral total knee replacement
- >18 years of age
- Participants must be able to speak and understand Danish
- Participants must be able to give informed consent and be cognitively intact
- Participants must be able to complete all post-operative controls
- Participants must not have severe comorbidities, American Society of Anesthesiologists (ASA) score ≤ 3
- Clinically suitable to receive a CR implant (no severe deformity and/or ligament instability)
Who cannot take part
- Revision knee replacement surgery
- Prior surgery on the affected knee that includes osteosynthesis, Anterior cruciate ligament (ACL) and/or Posterior cruciate ligament (PCL) and/or collateral ligament surgery. Arthroscopy with meniscectomy / cartilage surgery / house cleaning is allowed
- Patients will be excluded intraoperative if CR implant is not suitable
- Terminal illness
- Altered pain perception and / or neurologic affection due to diabetes or other disorders
- Rheumatoid Arthritis (RA)
- Traumatic etiology
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
A multicenter, prospective randomized controlled trial comparing the Persona knee system to the Nexgen knee system in total knee arthroplasty.
The 2 groups in the trial
- Persona CRExisting treatment, for comparison
Patients who received a Persona CR total knee implant
Treatment: Persona total knee system
- NexGen CRExisting treatment, for comparison
Patients who received a NexGen CR total knee implant
Treatment: Nexgen total knee system
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- A Multicenter Prospective Randomized Control Study on Persona Total Knee System vs NexGen Total Knee System in Total Knee Arthroplasty
- Record updated
- 12 May 2026