Study of Food Aversion in Patients With Anorexia Nervosa
Key facts
- Who runs it
- University of California, San Diego
- Where
- La Jolla, United StatesSee the siteAlso in 1 other country, 1 site
- Trial code
- Status
- Recruiting
- People taking part
- 300 people, planned
- Started
- 10 Nov 2016
- Expected to end
- 31 Dec 2027
- Type of study
- Interventional, 3 groups
- Treatments tested
- A breakfast sandwich
- Record updated
- 31 March 2026
Who can take part
- Age
- 18 years to 55 years
- Sex
- Women only
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 4 criteriaShow less
Who can take part
- Ill AN subjects will meet current Diagnostic and Statistical Manual of Mental Disorders (DSM V) diagnosis of AN, body mass index (BMI) between 11 kg/m² and 17.5 kg/m², or BMI > 17.5 kg/m² with active eating disorder symptoms
- Recovered AN must meet the following criteria at time of study entry: 1) Current or past DSM V diagnosis of AN; 2) BMI between 18.5 kg/m2 and 30 kg/m2; 3) Having maintained a BMI of >18.5 for at least one year
- Control must be healthy adolescent or woman negative on our screen for AN, other Axis I psychiatric illnesses, and having maintained a BMI of between 18.5-30 kg/m² since the age of 18
Who cannot take part
- Exclusion criteria for AN and control subjects include: Organic brain syndrome, schizophrenia and schizoaffective disorder, untreated thyroid disease, renal disease, hepatic disease, and the regular use of fish-oil containing supplements within the last three months of the study. All pregnant and lactating individuals will be excluded
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 55 years old?
Where in United States
Also in 1 other country, 1 site
- UC San Diego - Altman Clinical and Translational Research InstituteLa Jolla, United StatesContact: P. Betty Shih, MPM, PhDTaking people
About the trial
What the trial wants to find out
This study uses a meal-challenge protocol to assess if patients with anorexia nervosa show a differential metabolism in response to food in comparison to healthy controls. This study determines how heritable and biochemical factors influence food metabolism in anorexia nervosa in order to develop more effective treatment strategies.
The 3 groups in the trial
- Anorexia nervosa IOther group
Anorexia nervosa with BMI \<=17.5 kg/m² or BMI \>17.5 kg/m² with regular binge-purge episodes
Treatment: A breakfast sandwich
- Anorexia nervosa IIOther group
Anorexia nervosa with BMI \> 18.5 kg/m² for at least 12 months.
Treatment: A breakfast sandwich
- ControlsOther group
Healthy control women
Treatment: A breakfast sandwich
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Solving EPHX2 and Polyunsaturated Fatty Acid Interactions in Anorexia Nervosa
- Fit questions
- Built from NCT03100656, who can take part
- Record updated
- 31 March 2026