Taking people in United StatesPhase 3
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
Key facts
- Where
- ‘Aiea, Aberdeen, Aitkin, Albuquerque, Allentown, Alton, American Fork, Anaconda, Anchorage, Ann Arbor, Antioch, Arroyo Grande, Ashland, Atlanta, Augusta, Aurora, Baker City, Ballwin, Baltimore, Baton Rouge, Battle Creek, Bellevue, Bellingham, Bend, Bethlehem, Billings, Birmingham, Boiling Springs, Boise, Bolivar, Boston, Boulder, Bozeman, Brainerd, Branson, Brighton, Buffalo, Burbank, Burnsville, Burr Ridge, Butte, Caldwell, Cambridge, Canton, Caro, Carroll, Carson City, Cedar City, Centennial, Centralia, Chapel Hill, Chelsea, Cheyenne, Chicago, Cincinnati, City of Saint Peters, Clackamas, Clarkston, Cleveland, Clinton, Clovis, Cody, Coeur d'Alene, Columbia, Columbus, Coon Rapids, Coos Bay, Costa Mesa, Creve Coeur, Deer River, Denver, Des Moines, Detroit, Detroit Lakes, Dublin, Duluth, Durham, Easley, East China Township, East Stroudsburg, Edina, Edmonds, Emmett, Englewood, Evanston, Everett, Fairbanks, Fairfax, Falls Church, Fargo, Farmington Hills, Fergus Falls, Flint, Fort Dodge, Fort Lauderdale, Fort Smith, Fosston, Fremont, Fresno, Fridley, Fruitland, Garden City, Glenview, Golden, Grand Junction, Grand Rapids, Great Bend, Great Falls, Greeley, Greenville, Greer, Grosse Pointe Woods, Hartford, Hayward, Hazleton, Henderson, Hibbing, Highland Park, Hilo, Hollywood, Homer Glen, Honolulu, Houston, Iowa City, Irvine, Issaquah, Jamestown, Joplin, Kalamazoo, Kalispell, Kansas City, Kennewick, Kingman, Lacey, Lafayette, Lake Forest, Lake Success, Lakewood, Lansing, Las Vegas, Lawrence, Lexington, Lihue, Lisle, Littleton, Livonia, Logan, Lone Tree, Longview, Loveland, Lubbock, Macomb, Madison, Manhasset, Maple Grove, Maplewood, Marlette, Marshfield, Maywood, Melrose Park, Meridian, Miami, Milwaukee, Minneapolis, Missoula, Modesto, Monticello, Mount Vernon, Murray, Muskegon, Nampa, New Haven, New Hyde Park, New Lenox, New Orleans, New Richmond, New Ulm, New York, Newberg, Niles, Norton Shores, Oakland, Ogden, Oklahoma City, Omaha, Ontario, Orange, Orland Park, Orlando, Pahrump, Palo Alto, Park Rapids, Pembroke Pines, Philadelphia, Phoenix, Pittsburgh, Pontiac, Port Townsend, Portland, Post Falls, Princeton, Providence, Provo, Rancho Cordova, Redmond, Redwood City, Reed City, Reno, Renton, Richmond, Riverton, Robbinsdale, Rochester, Rochester Hills, Rohnert Park, Rolla, Roseville, Sacramento, Saginaw, Saint Joseph, Saint Louis Park, Saint Paul, Salt Lake City, San Francisco, San Jose, San Leandro, San Rafael, Sandpoint, Sandstone, Santa Clara, Santa Rosa, Scottsdale, Seattle, Sedro-Woolley, Seneca, Shakopee, Shelton, Sheridan, South San Francisco, Spooner, Springfield, St Louis, St. George, Sterling Heights, Stillwater, Stockton, Stony Brook, Superior, Syracuse, Tawas City, Thornton, Traverse City, Twin Falls, Vacaville, Vallejo, Vancouver, Verona, Virginia, Waconia, Walla Walla, Walnut Creek, Warren, Washington, West Branch, West Chester, West Des Moines, Westwood, Wheat Ridge, Wichita, Willmar, Winston-Salem, Woodbury, Wyoming, Yakima, Yelm, and Ypsilanti, United StatesSee the 455 sites
- Phase
- Phase 3
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 39 years old?
Source: NCT03150693, who can take part
Where in United States
- Pali Momi Medical Center‘Aiea, United StatesTaking people
- Hawaii Cancer Care - Westridge‘Aiea, United StatesNo longer taking part
- Queen's Cancer Center - Pearlridge‘Aiea, United StatesNo longer taking part
- The Cancer Center of Hawaii-Pali Momi‘Aiea, United StatesNo longer taking part
- Providence Regional Cancer System-AberdeenAberdeen, United StatesNo longer taking part
- Riverwood Healthcare CenterAitkin, United StatesNo longer taking part
- University of New Mexico Cancer CenterAlbuquerque, United StatesNo longer taking part
- Lehigh Valley Hospital-Cedar CrestAllentown, United StatesTaking people
- OSF Saint Anthony's Health CenterAlton, United StatesNo longer taking part
- American Fork Hospital / Huntsman Intermountain Cancer CenterAmerican Fork, United StatesNo longer taking part
- Community Hospital of AnacondaAnaconda, United StatesTaking people
- Alaska Breast Care and Surgery LLCAnchorage, United StatesNo longer taking part
- Alaska Oncology and Hematology LLCAnchorage, United StatesNo longer taking part
- Alaska Women's Cancer CareAnchorage, United StatesNo longer taking part
- Anchorage Associates in Radiation MedicineAnchorage, United StatesNo longer taking part
- Anchorage Oncology CentreAnchorage, United StatesNo longer taking part
- Anchorage Radiation Therapy CenterAnchorage, United StatesNo longer taking part
- Katmai Oncology GroupAnchorage, United StatesNo longer taking part
- Providence Alaska Medical CenterAnchorage, United StatesNo longer taking part
- Trinity Health Saint Joseph Mercy Hospital Ann ArborAnn Arbor, United StatesTaking people
- Kaiser Permanente-Deer Valley Medical CenterAntioch, United StatesTaking people
- PCR OncologyArroyo Grande, United StatesNo longer taking part
- Duluth Clinic AshlandAshland, United StatesNo longer taking part
- Northwest Wisconsin Cancer CenterAshland, United StatesNo longer taking part
- Emory University Hospital/Winship Cancer InstituteAtlanta, United StatesTaking people
- Augusta University Medical CenterAugusta, United StatesTaking people
- Rocky Mountain Cancer Centers-AuroraAurora, United StatesNo longer taking part
- The Medical Center of AuroraAurora, United StatesNo longer taking part
- Saint Alphonsus Cancer Care Center-Baker CityBaker City, United StatesNo longer taking part
- Mercy Oncology and Hematology - Clayton-ClarksonBallwin, United StatesNo longer taking part
- University of Maryland/Greenebaum Cancer CenterBaltimore, United StatesTaking people
- Medical Center of Baton RougeBaton Rouge, United StatesNo longer taking part
- Ochsner Health Center-SummaBaton Rouge, United StatesNo longer taking part
- Ochsner High GroveBaton Rouge, United StatesNo longer taking part
- Bronson Battle CreekBattle Creek, United StatesNo longer taking part
- Nebraska Medicine-BellevueBellevue, United StatesTaking people
- Overlake Medical CenterBellevue, United StatesNo longer taking part
- PeaceHealth Saint Joseph Medical CenterBellingham, United StatesNo longer taking part
- Saint Charles Health SystemBend, United StatesNo longer taking part
- Lehigh Valley Hospital - MuhlenbergBethlehem, United StatesTaking people
- Billings Clinic Cancer CenterBillings, United StatesTaking people
- Saint Vincent Frontier Cancer CenterBillings, United StatesNo longer taking part
- Saint Vincent HealthcareBillings, United StatesNo longer taking part
- University of Alabama at Birmingham Cancer CenterBirmingham, United StatesNo longer taking part
- Prisma Health Cancer Institute - SpartanburgBoiling Springs, United StatesTaking people
- Saint Alphonsus Cancer Care Center-BoiseBoise, United StatesTaking people
- Saint Luke's Cancer Institute - BoiseBoise, United StatesTaking people
- Central Care Cancer Center - BolivarBolivar, United StatesNo longer taking part
- Beth Israel Deaconess Medical CenterBoston, United StatesNo longer taking part
- Dana-Farber Cancer InstituteBoston, United StatesNo longer taking part
- Massachusetts General Hospital Cancer CenterBoston, United StatesNo longer taking part
- Boulder Community Foothills HospitalBoulder, United StatesNo longer taking part
- Rocky Mountain Cancer Centers-BoulderBoulder, United StatesNo longer taking part
- Bozeman Health Deaconess HospitalBozeman, United StatesTaking people
- Essentia Health Saint Joseph's Medical CenterBrainerd, United StatesNo longer taking part
- Cox Cancer Center BransonBranson, United StatesNo longer taking part
- Trinity Health IHA Medical Group Hematology Oncology - BrightonBrighton, United StatesTaking people
- Trinity Health Medical Center - BrightonBrighton, United StatesTaking people
- Roswell Park Cancer InstituteBuffalo, United StatesTaking people
- Providence Saint Joseph Medical Center/Disney Family Cancer CenterBurbank, United StatesNo longer taking part
- Fairview Ridges HospitalBurnsville, United StatesNo longer taking part
- Minnesota Oncology - BurnsvilleBurnsville, United StatesNo longer taking part
- Loyola Center for Health at Burr RidgeBurr Ridge, United StatesNo longer taking part
- Saint James Community Hospital and Cancer Treatment CenterButte, United StatesNo longer taking part
- Saint Alphonsus Cancer Care Center-CaldwellCaldwell, United StatesTaking people
- Cambridge Medical CenterCambridge, United StatesNo longer taking part
- Trinity Health IHA Medical Group Hematology Oncology - CantonCanton, United StatesTaking people
- Trinity Health Medical Center - CantonCanton, United StatesTaking people
- Caro Cancer CenterCaro, United StatesNo longer taking part
- Saint Anthony Regional HospitalCarroll, United StatesNo longer taking part
- Carson Tahoe Regional Medical CenterCarson City, United StatesNo longer taking part
- Sandra L Maxwell Cancer CenterCedar City, United StatesNo longer taking part
- Rocky Mountain Cancer Centers - CentennialCentennial, United StatesNo longer taking part
- Providence Regional Cancer System-CentraliaCentralia, United StatesNo longer taking part
- UNC Lineberger Comprehensive Cancer CenterChapel Hill, United StatesTaking people
- Chelsea HospitalChelsea, United StatesTaking people
- Trinity Health IHA Medical Group Hematology Oncology - Chelsea HospitalChelsea, United StatesTaking people
- Cheyenne Regional Medical Center-WestCheyenne, United StatesNo longer taking part
- Northwestern UniversityChicago, United StatesTaking people
- Rush MD Anderson Cancer CenterChicago, United StatesTaking people
- University of Chicago Comprehensive Cancer CenterChicago, United StatesTaking people
- University of IllinoisChicago, United StatesTaking people
- University of Cincinnati Cancer Center-UC Medical CenterCincinnati, United StatesTaking people
- Siteman Cancer Center at Saint Peters HospitalCity of Saint Peters, United StatesTaking people
- Clackamas Radiation Oncology CenterClackamas, United StatesNo longer taking part
- Providence Cancer Institute Clackamas ClinicClackamas, United StatesNo longer taking part
- Hematology Oncology Consultants-ClarkstonClarkston, United StatesNo longer taking part
- Newland Medical Associates-ClarkstonClarkston, United StatesNo longer taking part
- Case Western Reserve UniversityCleveland, United StatesTaking people
- Cleveland Clinic FoundationCleveland, United StatesTaking people
- Prisma Health Cancer Institute - LaurensClinton, United StatesNo longer taking part
- Community Cancer InstituteClovis, United StatesTaking people
- University Oncology AssociatesClovis, United StatesNo longer taking part
- Billings Clinic-CodyCody, United StatesNo longer taking part
- Kootenai Health - Coeur d'AleneCoeur d'Alene, United StatesTaking people
- Prisma Health Richland HospitalColumbia, United StatesTaking people
- Ohio State University Comprehensive Cancer CenterColumbus, United StatesTaking people
- Mercy HospitalCoon Rapids, United StatesNo longer taking part
- Bay Area HospitalCoos Bay, United StatesNo longer taking part
- UC Irvine Health Cancer Center-NewportCosta Mesa, United StatesTaking people
- Siteman Cancer Center at West County HospitalCreve Coeur, United StatesTaking people
- Essentia Health - Deer River ClinicDeer River, United StatesNo longer taking part
- Cancer Center of Colorado at Sloan's LakeDenver, United StatesNo longer taking part
- Colorado Blood Cancer InstituteDenver, United StatesNo longer taking part
- National Jewish Health-Main CampusDenver, United StatesNo longer taking part
- Presbyterian - Saint Lukes Medical Center - Health OneDenver, United StatesNo longer taking part
- Rocky Mountain Cancer Centers-MidtownDenver, United StatesNo longer taking part
- Rocky Mountain Cancer Centers-RoseDenver, United StatesNo longer taking part
- Rose Medical CenterDenver, United StatesNo longer taking part
- Saint Joseph Hospital - Cancer Centers of ColoradoDenver, United StatesNo longer taking part
- The Women's Imaging CenterDenver, United StatesNo longer taking part
- Western Surgical CareDenver, United StatesNo longer taking part
- Blank Children's HospitalDes Moines, United StatesNo longer taking part
- Broadlawns Medical CenterDes Moines, United StatesNo longer taking part
- Iowa Lutheran HospitalDes Moines, United StatesNo longer taking part
- Iowa Methodist Medical CenterDes Moines, United StatesNo longer taking part
- UI Health Care Mission Cancer and Blood - Des Moines ClinicDes Moines, United StatesNo longer taking part
- Wayne State University/Karmanos Cancer InstituteDetroit, United StatesTaking people
- Henry Ford Health Saint John HospitalDetroit, United StatesNo longer taking part
- Essentia Health Saint Mary's - Detroit Lakes ClinicDetroit Lakes, United StatesNo longer taking part
- Kaiser Permanente DublinDublin, United StatesTaking people
- Essentia Health Cancer CenterDuluth, United StatesTaking people
- Essentia Health Saint Mary's Medical CenterDuluth, United StatesNo longer taking part
- Miller-Dwan HospitalDuluth, United StatesNo longer taking part
- Duke University Medical CenterDurham, United StatesNo longer taking part
- Prisma Health Cancer Institute - EasleyEasley, United StatesTaking people
- Henry Ford River District HospitalEast China Township, United StatesNo longer taking part
- Pocono Medical CenterEast Stroudsburg, United StatesNo longer taking part
- Fairview Southdale HospitalEdina, United StatesNo longer taking part
- Swedish Cancer Institute-EdmondsEdmonds, United StatesTaking people
- Walter Knox Memorial HospitalEmmett, United StatesNo longer taking part
- Mountain Blue Cancer Care Center - SwedishEnglewood, United StatesNo longer taking part
- Rocky Mountain Cancer Centers - SwedishEnglewood, United StatesNo longer taking part
- Swedish Medical CenterEnglewood, United StatesNo longer taking part
- The Melanoma and Skin Cancer InstituteEnglewood, United StatesNo longer taking part
- NorthShore University HealthSystem-Evanston HospitalEvanston, United StatesTaking people
- Providence Regional Cancer PartnershipEverett, United StatesNo longer taking part
- Fairbanks Memorial HospitalFairbanks, United StatesNo longer taking part
- Inova Schar Cancer InstituteFairfax, United StatesNo longer taking part
- Inova Fairfax HospitalFalls Church, United StatesNo longer taking part
- Essentia Health Cancer Center-South University ClinicFargo, United StatesNo longer taking part
- Weisberg Cancer Treatment CenterFarmington Hills, United StatesTaking people
- Lake Region Healthcare Corporation-Cancer CareFergus Falls, United StatesNo longer taking part
- Cancer Hematology Centers - FlintFlint, United StatesTaking people
- Genesys Hurley Cancer InstituteFlint, United StatesTaking people
- Hurley Medical CenterFlint, United StatesTaking people
- Genesee Hematology Oncology PCFlint, United StatesNo longer taking part
- UI Healthcare Mission Cancer and Blood - Fort DodgeFort Dodge, United StatesNo longer taking part
- Holy Cross HospitalFort Lauderdale, United StatesNo longer taking part
- Mercy Hospital Fort SmithFort Smith, United StatesNo longer taking part
- Essentia Health - FosstonFosston, United StatesNo longer taking part
- Kaiser Permanente-FremontFremont, United StatesTaking people
- Kaiser Permanente Fresno Orchard PlazaFresno, United StatesTaking people
- Kaiser Permanente-FresnoFresno, United StatesTaking people
- Fresno Cancer CenterFresno, United StatesNo longer taking part
- Unity HospitalFridley, United StatesNo longer taking part
- Saint Luke's Cancer Institute - FruitlandFruitland, United StatesTaking people
- Central Care Cancer Center - Garden CityGarden City, United StatesNo longer taking part
- NorthShore University HealthSystem-Glenbrook HospitalGlenview, United StatesTaking people
- National Jewish Health-Western Hematology OncologyGolden, United StatesNo longer taking part
- Saint Mary's Hospital and Regional Medical CenterGrand Junction, United StatesNo longer taking part
- Corewell Health Grand Rapids Hospitals - Butterworth HospitalGrand Rapids, United StatesTaking people
- Trinity Health Grand Rapids HospitalGrand Rapids, United StatesTaking people
- Corewell Health Grand Rapids Hospitals - Helen DeVos Children's HospitalGrand Rapids, United StatesNo longer taking part
- Central Care Cancer Center - Great BendGreat Bend, United StatesNo longer taking part
- Benefis Sletten Cancer InstituteGreat Falls, United StatesTaking people
- Great Falls ClinicGreat Falls, United StatesNo longer taking part
- Banner North Colorado Medical CenterGreeley, United StatesNo longer taking part
- East Carolina UniversityGreenville, United StatesTaking people
- Prisma Health Cancer Institute - ButternutGreenville, United StatesTaking people
- Prisma Health Cancer Institute - EastsideGreenville, United StatesTaking people
- Prisma Health Cancer Institute - FarisGreenville, United StatesTaking people
- Prisma Health Greenville Memorial HospitalGreenville, United StatesTaking people
- Saint Francis Cancer CenterGreenville, United StatesTaking people
- Saint Francis HospitalGreenville, United StatesTaking people
- BI-LO Charities Children's Cancer CenterGreenville, United StatesNo longer taking part
- Prisma Health Cancer Institute - GreerGreer, United StatesTaking people
- Henry Ford Saint John Hospital - AcademicGrosse Pointe Woods, United StatesNo longer taking part
- Henry Ford Saint John Hospital - BreastGrosse Pointe Woods, United StatesNo longer taking part
- Henry Ford Saint John Hospital - Van ElslanderGrosse Pointe Woods, United StatesNo longer taking part
- Smilow Cancer Hospital Care Center at Saint FrancisHartford, United StatesNo longer taking part
- Essentia Health-Hayward ClinicHayward, United StatesNo longer taking part
- Lehigh Valley Hospital-HazletonHazleton, United StatesNo longer taking part
- Cancer and Blood Specialists-HendersonHenderson, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada - HendersonHenderson, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada-Horizon RidgeHenderson, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada-Southeast HendersonHenderson, United StatesNo longer taking part
- Las Vegas Cancer Center-HendersonHenderson, United StatesNo longer taking part
- Las Vegas Urology - Green ValleyHenderson, United StatesNo longer taking part
- Las Vegas Urology - PebbleHenderson, United StatesNo longer taking part
- Oncology Las Vegas - HendersonHenderson, United StatesNo longer taking part
- Urology Specialists of Nevada - Green ValleyHenderson, United StatesNo longer taking part
- Essentia Health Hibbing ClinicHibbing, United StatesNo longer taking part
- NorthShore University HealthSystem-Highland Park HospitalHighland Park, United StatesTaking people
- Island Urology-HiloHilo, United StatesNo longer taking part
- Memorial Regional Hospital/Joe DiMaggio Children's HospitalHollywood, United StatesTaking people
- Loyola Medicine Homer GlenHomer Glen, United StatesNo longer taking part
- Kapiolani Medical Center for Women and ChildrenHonolulu, United StatesTaking people
- Straub Clinic and HospitalHonolulu, United StatesTaking people
- Hawaii Cancer Care Inc - Waterfront PlazaHonolulu, United StatesNo longer taking part
- Hawaii Cancer Care Inc-LilihaHonolulu, United StatesNo longer taking part
- Island UrologyHonolulu, United StatesNo longer taking part
- Kaiser Permanente Moanalua Medical CenterHonolulu, United StatesNo longer taking part
- Kuakini Medical CenterHonolulu, United StatesNo longer taking part
- Queen's Cancer Cenrer - POB IHonolulu, United StatesNo longer taking part
- Queen's Cancer Center - KuakiniHonolulu, United StatesNo longer taking part
- Queen's Medical CenterHonolulu, United StatesNo longer taking part
- The Cancer Center of Hawaii-LilihaHonolulu, United StatesNo longer taking part
- University of Hawaii Cancer CenterHonolulu, United StatesNo longer taking part
- Houston Methodist HospitalHouston, United StatesTaking people
- University of Iowa/Holden Comprehensive Cancer CenterIowa City, United StatesTaking people
- UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory CareIrvine, United StatesTaking people
- Swedish Cancer Institute-IssaquahIssaquah, United StatesNo longer taking part
- Essentia Health - Jamestown ClinicJamestown, United StatesNo longer taking part
- Freeman Health SystemJoplin, United StatesNo longer taking part
- Mercy Hospital JoplinJoplin, United StatesNo longer taking part
- Beacon Kalamazoo Cancer CenterKalamazoo, United StatesTaking people
- Bronson Methodist HospitalKalamazoo, United StatesTaking people
- West Michigan Cancer CenterKalamazoo, United StatesTaking people
- Beacon KalamazooKalamazoo, United StatesNo longer taking part
- Logan Health Medical CenterKalispell, United StatesTaking people
- University of Kansas Cancer CenterKansas City, United StatesTaking people
- Kadlec Clinic Hematology and OncologyKennewick, United StatesNo longer taking part
- Kingman Regional Medical CenterKingman, United StatesNo longer taking part
- Providence Regional Cancer System-LaceyLacey, United StatesNo longer taking part
- Good Samaritan Hospital - Cancer Centers of ColoradoLafayette, United StatesNo longer taking part
- Northwestern Medicine Lake Forest HospitalLake Forest, United StatesNo longer taking part
- Northwell Health/Center for Advanced MedicineLake Success, United StatesTaking people
- Rocky Mountain Cancer Centers-LakewoodLakewood, United StatesNo longer taking part
- University of Michigan Health - Sparrow LansingLansing, United StatesNo longer taking part
- Alliance for Childhood Diseases/Cure 4 the Kids FoundationLas Vegas, United StatesNo longer taking part
- Ann M Wierman MD LTDLas Vegas, United StatesNo longer taking part
- Comprehensive Cancer Centers of NevadaLas Vegas, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada - Central ValleyLas Vegas, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada - NorthwestLas Vegas, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada - Town CenterLas Vegas, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada-SummerlinLas Vegas, United StatesNo longer taking part
- Desert West SurgeryLas Vegas, United StatesNo longer taking part
- Hope Cancer Care of NevadaLas Vegas, United StatesNo longer taking part
- Las Vegas Cancer Center-Medical CenterLas Vegas, United StatesNo longer taking part
- Las Vegas Prostate Cancer CenterLas Vegas, United StatesNo longer taking part
- Las Vegas Urology - Cathedral RockLas Vegas, United StatesNo longer taking part
- Las Vegas Urology - PecosLas Vegas, United StatesNo longer taking part
- Las Vegas Urology - Smoke RanchLas Vegas, United StatesNo longer taking part
- Las Vegas Urology - SunsetLas Vegas, United StatesNo longer taking part
- Oncology Las Vegas - TenayaLas Vegas, United StatesNo longer taking part
- OptumCare Cancer Care at CharlestonLas Vegas, United StatesNo longer taking part
- OptumCare Cancer Care at Fort ApacheLas Vegas, United StatesNo longer taking part
- OptumCare Cancer Care at MountainViewLas Vegas, United StatesNo longer taking part
- Radiation Oncology Centers of Nevada CentralLas Vegas, United StatesNo longer taking part
- Radiation Oncology Centers of Nevada SoutheastLas Vegas, United StatesNo longer taking part
- Summerlin Hospital Medical CenterLas Vegas, United StatesNo longer taking part
- Sunrise Hospital and Medical CenterLas Vegas, United StatesNo longer taking part
- University Cancer CenterLas Vegas, United StatesNo longer taking part
- University Medical Center of Southern NevadaLas Vegas, United StatesNo longer taking part
- Urology Specialists of Nevada - CentralLas Vegas, United StatesNo longer taking part
- Urology Specialists of Nevada - NorthwestLas Vegas, United StatesNo longer taking part
- Urology Specialists of Nevada - SouthwestLas Vegas, United StatesNo longer taking part
- Lawrence Memorial HospitalLawrence, United StatesNo longer taking part
- University of Kentucky/Markey Cancer CenterLexington, United StatesTaking people
- Wilcox Memorial Hospital and Kauai Medical ClinicLihue, United StatesNo longer taking part
- Rush MD Anderson Cancer Center at Rush LisleLisle, United StatesNo longer taking part
- Rocky Mountain Cancer Centers-LittletonLittleton, United StatesNo longer taking part
- Trinity Health Saint Mary Mercy Livonia HospitalLivonia, United StatesTaking people
- Hope Cancer ClinicLivonia, United StatesNo longer taking part
- Logan Regional HospitalLogan, United StatesNo longer taking part
- Rocky Mountain Cancer Centers-Sky RidgeLone Tree, United StatesNo longer taking part
- Sky Ridge Medical CenterLone Tree, United StatesNo longer taking part
- PeaceHealth Saint John Medical CenterLongview, United StatesNo longer taking part
- Banner North Colorado Medical Center - Loveland CampusLoveland, United StatesNo longer taking part
- Covenant Medical Center-LakesideLubbock, United StatesNo longer taking part
- Henry Ford Saint John Hospital - Macomb MedicalMacomb, United StatesTaking people
- Henry Ford Warren Hospital - Breast MacombMacomb, United StatesNo longer taking part
- University of Wisconsin Carbone Cancer Center - Eastpark Medical CenterMadison, United StatesTaking people
- University of Wisconsin Carbone Cancer Center - University HospitalMadison, United StatesTaking people
- North Shore University HospitalManhasset, United StatesTaking people
- Fairview Clinics and Surgery Center Maple GroveMaple Grove, United StatesNo longer taking part
- Minnesota Oncology Hematology PA-MaplewoodMaplewood, United StatesNo longer taking part
- Saint John's Hospital - HealtheastMaplewood, United StatesNo longer taking part
- Saint Mary's Oncology/Hematology Associates of MarletteMarlette, United StatesNo longer taking part
- Marshfield Medical Center-MarshfieldMarshfield, United StatesTaking people
- Loyola University Medical CenterMaywood, United StatesTaking people
- Marjorie Weinberg Cancer Center at Loyola-GottliebMelrose Park, United StatesNo longer taking part
- Saint Luke's Cancer Institute - MeridianMeridian, United StatesTaking people
- Idaho Urologic Institute-MeridianMeridian, United StatesNo longer taking part
- Miami Cancer InstituteMiami, United StatesNo longer taking part
- Medical College of WisconsinMilwaukee, United StatesTaking people
- Abbott-Northwestern HospitalMinneapolis, United StatesTaking people
- Health Partners IncMinneapolis, United StatesNo longer taking part
- Hennepin County Medical CenterMinneapolis, United StatesNo longer taking part
- Community Medical CenterMissoula, United StatesTaking people
- Saint Patrick Hospital - Community HospitalMissoula, United StatesNo longer taking part
- Kaiser Permanente- Modesto MOB IIModesto, United StatesTaking people
- Kaiser Permanente-ModestoModesto, United StatesTaking people
- Monticello Cancer CenterMonticello, United StatesNo longer taking part
- SSM Health Good SamaritanMount Vernon, United StatesNo longer taking part
- Intermountain Medical CenterMurray, United StatesNo longer taking part
- Trinity Health Muskegon HospitalMuskegon, United StatesNo longer taking part
- Saint Alphonsus Cancer Care Center-NampaNampa, United StatesTaking people
- Saint Luke's Cancer Institute - NampaNampa, United StatesTaking people
- Yale UniversityNew Haven, United StatesTaking people
- Smilow Cancer Center/Yale-New Haven HospitalNew Haven, United StatesNo longer taking part
- Long Island Jewish Medical CenterNew Hyde Park, United StatesTaking people
- UC Comprehensive Cancer Center at Silver CrossNew Lenox, United StatesTaking people
- Ochsner Medical Center JeffersonNew Orleans, United StatesNo longer taking part
- Cancer Center of Western WisconsinNew Richmond, United StatesNo longer taking part
- New Ulm Medical CenterNew Ulm, United StatesNo longer taking part
- Mount Sinai HospitalNew York, United StatesTaking people
- NYP/Weill Cornell Medical CenterNew York, United StatesTaking people
- Providence Newberg Medical CenterNewberg, United StatesTaking people
- Corewell Health Lakeland Hospitals - Niles HospitalNiles, United StatesTaking people
- Cancer and Hematology Centers of Western Michigan - Norton ShoresNorton Shores, United StatesNo longer taking part
- Kaiser Permanente-OaklandOakland, United StatesTaking people
- Kaiser Permanente Oakland-BroadwayOakland, United StatesNo longer taking part
- McKay-Dee Hospital CenterOgden, United StatesNo longer taking part
- University of Oklahoma Health Sciences CenterOklahoma City, United StatesTaking people
- Mercy Hospital Oklahoma CityOklahoma City, United StatesNo longer taking part
- Nebraska Medicine-Village PointeOmaha, United StatesTaking people
- University of Nebraska Medical CenterOmaha, United StatesTaking people
- Saint Alphonsus Cancer Care Center-OntarioOntario, United StatesTaking people
- UC Irvine Health- Chao Family Comprehensive Cancer CenterOrange, United StatesTaking people
- University of Chicago Medicine-Orland ParkOrland Park, United StatesTaking people
- Orlando Health Cancer InstituteOrlando, United StatesTaking people
- Hope Cancer Care of Nevada-PahrumpPahrump, United StatesNo longer taking part
- Stanford Cancer Institute Palo AltoPalo Alto, United StatesTaking people
- Essentia Health - Park RapidsPark Rapids, United StatesNo longer taking part
- Memorial Hospital WestPembroke Pines, United StatesNo longer taking part
- Thomas Jefferson University HospitalPhiladelphia, United StatesTaking people
- University of Pennsylvania/Abramson Cancer CenterPhiladelphia, United StatesTaking people
- Mayo Clinic Hospital in ArizonaPhoenix, United StatesNo longer taking part
- UPMC Hillman Cancer CenterPittsburgh, United StatesNo longer taking part
- Trinity Health Saint Joseph Mercy Oakland HospitalPontiac, United StatesTaking people
- Hope Cancer CenterPontiac, United StatesNo longer taking part
- Michigan Healthcare Professionals PontiacPontiac, United StatesNo longer taking part
- Trinity Health IHA Medical Group-Alice Gustafson CenterPontiac, United StatesNo longer taking part
- Jefferson HealthcarePort Townsend, United StatesNo longer taking part
- Oregon Health and Science UniversityPortland, United StatesTaking people
- Providence Portland Medical CenterPortland, United StatesTaking people
- Providence Saint Vincent Medical CenterPortland, United StatesTaking people
- Kootenai Clinic Cancer Services - Post FallsPost Falls, United StatesTaking people
- Fairview Northland Medical CenterPrinceton, United StatesNo longer taking part
- Rhode Island HospitalProvidence, United StatesTaking people
- Miriam HospitalProvidence, United StatesNo longer taking part
- Utah Valley Regional Medical CenterProvo, United StatesNo longer taking part
- Kaiser Permanente-Rancho Cordova Cancer CenterRancho Cordova, United StatesNo longer taking part
- Saint Charles Health System-RedmondRedmond, United StatesNo longer taking part
- Kaiser Permanente- Marshall Medical OfficesRedwood City, United StatesNo longer taking part
- Kaiser Permanente-Redwood CityRedwood City, United StatesNo longer taking part
- Corewell Health Reed City HospitalReed City, United StatesTaking people
- Radiation Oncology AssociatesReno, United StatesNo longer taking part
- Renown Regional Medical CenterReno, United StatesNo longer taking part
- Saint Mary's Regional Medical CenterReno, United StatesNo longer taking part
- Valley Medical CenterRenton, United StatesNo longer taking part
- Kaiser Permanente-RichmondRichmond, United StatesTaking people
- VCU Massey Comprehensive Cancer CenterRichmond, United StatesTaking people
- Riverton HospitalRiverton, United StatesNo longer taking part
- North Memorial Medical Health CenterRobbinsdale, United StatesNo longer taking part
- Mayo Clinic in RochesterRochester, United StatesTaking people
- University of RochesterRochester, United StatesTaking people
- Henry Ford Rochester HospitalRochester Hills, United StatesNo longer taking part
- Rohnert Park Cancer CenterRohnert Park, United StatesNo longer taking part
- Mercy Clinic-Rolla-Cancer and HematologyRolla, United StatesNo longer taking part
- Phelps Health Delbert Day Cancer InstituteRolla, United StatesNo longer taking part
- Kaiser Permanente-RosevilleRoseville, United StatesTaking people
- The Permanente Medical Group-Roseville Radiation OncologyRoseville, United StatesNo longer taking part
- Kaiser Permanente Downtown CommonsSacramento, United StatesTaking people
- Kaiser Permanente-South SacramentoSacramento, United StatesTaking people
- University of California Davis Comprehensive Cancer CenterSacramento, United StatesTaking people
- Kaiser Permanente Sacramento Medical CenterSacramento, United StatesNo longer taking part
- South Sacramento Cancer CenterSacramento, United StatesNo longer taking part
- MyMichigan Medical Center SaginawSaginaw, United StatesNo longer taking part
- Oncology Hematology Associates of Saginaw Valley PCSaginaw, United StatesNo longer taking part
- Corewell Health Lakeland Hospitals - Marie Yeager Cancer CenterSaint Joseph, United StatesTaking people
- Corewell Health Lakeland Hospitals - Saint Joseph HospitalSaint Joseph, United StatesNo longer taking part
- Heartland Regional Medical CenterSaint Joseph, United StatesNo longer taking part
- Park Nicollet Clinic - Saint Louis ParkSaint Louis Park, United StatesNo longer taking part
- Regions HospitalSaint Paul, United StatesNo longer taking part
- United HospitalSaint Paul, United StatesNo longer taking part
- Huntsman Cancer Institute/University of UtahSalt Lake City, United StatesTaking people
- LDS HospitalSalt Lake City, United StatesNo longer taking part
- Utah Cancer Specialists-Salt Lake CitySalt Lake City, United StatesNo longer taking part
- Kaiser Permanente-San FranciscoSan Francisco, United StatesTaking people
- Kaiser Permanente-Santa Teresa-San JoseSan Jose, United StatesTaking people
- Kaiser Permanente San LeandroSan Leandro, United StatesTaking people
- Kaiser San Rafael-GallinasSan Rafael, United StatesTaking people
- Kaiser Permanente-San RafaelSan Rafael, United StatesNo longer taking part
- Kootenai Clinic Cancer Services - SandpointSandpoint, United StatesTaking people
- Essentia Health SandstoneSandstone, United StatesNo longer taking part
- Kaiser Permanente Medical Center - Santa ClaraSanta Clara, United StatesTaking people
- Kaiser Permanente-Santa RosaSanta Rosa, United StatesTaking people
- Mayo Clinic in ArizonaScottsdale, United StatesNo longer taking part
- Swedish Medical Center-First HillSeattle, United StatesTaking people
- Kaiser Permanente WashingtonSeattle, United StatesNo longer taking part
- Pacific Gynecology SpecialistsSeattle, United StatesNo longer taking part
- Swedish Medical Center-Ballard CampusSeattle, United StatesNo longer taking part
- Swedish Medical Center-Cherry HillSeattle, United StatesNo longer taking part
- PeaceHealth United General Medical CenterSedro-Woolley, United StatesNo longer taking part
- Prisma Health Cancer Institute - SenecaSeneca, United StatesTaking people
- Saint Francis Regional Medical CenterShakopee, United StatesNo longer taking part
- Providence Regional Cancer System-SheltonShelton, United StatesNo longer taking part
- Welch Cancer CenterSheridan, United StatesNo longer taking part
- Kaiser Permanente-South San FranciscoSouth San Francisco, United StatesTaking people
- Kaiser Permanente Cancer Treatment CenterSouth San Francisco, United StatesNo longer taking part
- Essentia Health-Spooner ClinicSpooner, United StatesNo longer taking part
- CoxHealth South HospitalSpringfield, United StatesNo longer taking part
- Mercy Hospital SpringfieldSpringfield, United StatesNo longer taking part
- Mercy Hospital Saint LouisSt Louis, United StatesTaking people
- Mercy Hospital SouthSt Louis, United StatesTaking people
- Siteman Cancer Center-South CountySt Louis, United StatesTaking people
- Washington University School of MedicineSt Louis, United StatesTaking people
- Mercy Infusion Center - ChippewaSt Louis, United StatesNo longer taking part
- Saint George Regional Medical CenterSt. George, United StatesNo longer taking part
- Bhadresh Nayak MD PC-Sterling HeightsSterling Heights, United StatesNo longer taking part
- Lakeview HospitalStillwater, United StatesNo longer taking part
- Kaiser Permanente-StocktonStockton, United StatesTaking people
- Stony Brook University Medical CenterStony Brook, United StatesNo longer taking part
- Essentia Health Saint Mary's Hospital - SuperiorSuperior, United StatesNo longer taking part
- State University of New York Upstate Medical UniversitySyracuse, United StatesNo longer taking part
- MyMichigan Medical Center TawasTawas City, United StatesNo longer taking part
- National Jewish Health-Northern Hematology OncologyThornton, United StatesNo longer taking part
- Rocky Mountain Cancer Centers-ThorntonThornton, United StatesNo longer taking part
- Munson Medical CenterTraverse City, United StatesTaking people
- Saint Luke's Cancer Institute - Twin FallsTwin Falls, United StatesTaking people
- Kaiser Permanente Medical Center-VacavilleVacaville, United StatesTaking people
- Kaiser Permanente-VallejoVallejo, United StatesTaking people
- PeaceHealth Southwest Medical CenterVancouver, United StatesNo longer taking part
- Upstate Cancer Center at VeronaVerona, United StatesNo longer taking part
- Essentia Health Virginia ClinicVirginia, United StatesNo longer taking part
- Ridgeview Medical CenterWaconia, United StatesNo longer taking part
- Providence Saint Mary Regional Cancer CenterWalla Walla, United StatesNo longer taking part
- Kaiser Permanente-Walnut CreekWalnut Creek, United StatesTaking people
- Advanced Breast Care Center PLLCWarren, United StatesNo longer taking part
- Henry Ford Health Warren HospitalWarren, United StatesNo longer taking part
- Henry Ford Madison Heights Hospital - BreastWarren, United StatesNo longer taking part
- Henry Ford Warren Hospital - GLCMSWarren, United StatesNo longer taking part
- Macomb Hematology Oncology PCWarren, United StatesNo longer taking part
- Mercy Hospital WashingtonWashington, United StatesNo longer taking part
- Saint Mary's Oncology/Hematology Associates of West BranchWest Branch, United StatesNo longer taking part
- University of Cincinnati Cancer Center-West ChesterWest Chester, United StatesTaking people
- Methodist West HospitalWest Des Moines, United StatesNo longer taking part
- University of Kansas Hospital-Westwood Cancer CenterWestwood, United StatesTaking people
- Intermountain Health Lutheran HospitalWheat Ridge, United StatesNo longer taking part
- Cancer Center of Kansas - WichitaWichita, United StatesTaking people
- Ascension Via Christi Hospitals WichitaWichita, United StatesNo longer taking part
- Cancer Center of Kansas-Wichita Medical Arts TowerWichita, United StatesNo longer taking part
- Wesley Medical CenterWichita, United StatesNo longer taking part
- Rice Memorial HospitalWillmar, United StatesNo longer taking part
- Wake Forest University Health SciencesWinston-Salem, United StatesTaking people
- Minnesota Oncology Hematology PA-WoodburyWoodbury, United StatesNo longer taking part
- University of Michigan Health - WestWyoming, United StatesTaking people
- Fairview Lakes Medical CenterWyoming, United StatesNo longer taking part
- North Star Lodge Cancer Center at Yakima Valley Memorial HospitalYakima, United StatesNo longer taking part
- Providence Regional Cancer System-YelmYelm, United StatesNo longer taking part
- Huron Gastroenterology PCYpsilanti, United StatesTaking people
- Trinity Health IHA Medical Group Hematology Oncology Ann Arbor CampusYpsilanti, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Alliance for Clinical Trials in Oncology
- Trial code
- NCT03150693
- Record updated
- 3 November 2026
- Original description
This phase III trial studies the side effects of inotuzumab ozogamicin and how well it works when given with frontline chemotherapy in treating patients with newly diagnosed B acute lymphoblastic leukemia. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a chemotherapy drug called ozogamicin. Inotuzumab is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as CD22 receptors, and delivers ozogamicin to kill them. Chemotherapy drugs, such as [intervention], work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving inotuzumab ozogamicin with chemotherapy may work better in treating young adults with B acute lymphoblastic leukemia.Read full original descriptionShow less
A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzumab Ozogamicin (a Conjugated Anti-CD22 Monoclonal Antibody) to Frontline Therapy in Young Adults (Ages 18-39 Years) With Newly Diagnosed Precursor B-Cell ALL
This phase III trial studies the side effects of inotuzumab ozogamicin and how well it works when given with frontline chemotherapy in treating patients with newly diagnosed B acute lymphoblastic leukemia. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a chemotherapy drug called ozogamicin. Inotuzumab is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as CD22 receptors, and delivers ozogamicin to kill them. Chemotherapy drugs, such as [intervention], work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving inotuzumab ozogamicin with chemotherapy may work better in treating young adults with B acute lymphoblastic leukemia.
Inclusion: REGISTRATION ELIGIBILITY CRITERIA (STEP 1); Newly diagnosed patients with CD-22 positive B-cell acute lymphoblastic leukemia (WHO criteria) are eligible. Patients with Burkitt type ALL are NOT eligible; REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Single-dose intrathecal cytarabine is allowed prior to registration or prior to initiation of systematic therapy for patient convenience; this is usually done at the time of the diagnostic bone marrow or venous line placement to avoid a second lumbar puncture; systemic chemotherapy must begin within 72 hours of this intrathecal therapy; REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Age >= 18 years and < 40 years; REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Eastern Cooperative Oncology Group (ECOG) performance status 0-2; REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Aspartate aminotransferase (AST), alanine aminotransferase (ALT) =< 3 x upper limit of normal (ULN), unless suspected leukemic involvement of the liver; REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Direct bilirubin =< 3 x upper limit of normal (ULN), unless suspected leukemic involvement of the liver; REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Calculated (calc.) creatinine clearance >= 50 mL/min by Cockcroft-Gault; RANDOMIZATION ELIGIBILITY CRITERIA (STEP 2) CONFIRMATION OF TOLERABILITY AND PHASE III ONLY): Completion of remission induction therapy; RANDOMIZATION ELIGIBILITY CRITERIA (STEP 2) CONFIRMATION OF TOLERABILITY AND PHASE III ONLY):Patients with M2 marrow or better are eligible; patients with M3 or M4 marrow (greater than 25% lymphoblasts) will not be eligible to be randomized; Rating: M0, M1; Blast Cells (%): 0-5.0; Rating: M2; Blast Cells (%): 5.1-25.0; Rating: M3; Blast Cells (%): > 25-50; Rating: M4; Blast Cells (%): > 50.0; The term "blast cell" includes any cell that cannot be classified as a more mature normal element, and includes "leukemic cells," pathologic lymphocytes, and stem cells; RANDOMIZATION ELIGIBILITY CRITERIA (STEP 2) (CONFIRMATION OF TOLERABILITY AND PHASE III ONLY): Absolute neutrophil count (ANC) >= 750/mm\^3; RANDOMIZATION ELIGIBILITY CRITERIA (STEP 2) (CONFIRMATION OF TOLERABILITY AND PHASE III ONLY): Platelet count >= 75,000/mm\^3; RANDOMIZATION ELIGIBILITY CRITERIA (STEP 2) (CONFIRMATION OF TOLERABILITY AND PHASE III ONLY): Total bilirubin =< 1.5 x upper limit of normal (ULN), except for patients with known Gilbert's syndrome; RANDOMIZATION ELIGIBILITY CRITERIA (STEP 2) (CONFIRMATION OF TOLERABILITY AND PHASE III ONLY): Aspartate aminotransferase (AST) =< 8 x upper limit of normal (ULN).
Exclusion: REGISTRATION ELIGIBILITY CRITERIA (STEP 1): No prior therapy for ALL except for limited treatment (=< 7 days) with corticosteroids or hydroxyurea and a single dose of intrathecal cytarabine; however, patients who are being treated with chronic steroids for other reasons (for example, to treat asthma, autoimmune disorders, lupus, etc.) are eligible; REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Patients with down syndrome are excluded from this study due to the likelihood of excessive toxicity resulting; these patients should be treated in consultation with a pediatric oncologist; REGISTRATION ELIGIBILITY CRITERIA (STEP 1): No prior therapy for acute leukemia except emergency therapy (corticosteroids or hydroxyurea) for blast cell crisis, superior vena cava syndrome, or renal failure due to leukemic infiltration of the kidneys; when indicated, leukapheresis or exchange transfusion is recommended to reduce the WBC; REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Not pregnant and not nursing, because this study involves agents that have known genotoxic, mutagenic and teratogenic effects; therefore, for women of childbearing potential only, a negative urine or serum pregnancy test done =< 8 days prior to registration is required; REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Patients who have BCR-ABL fusion transcript determined by fluorescence in situ hybridization (FISH) or real time-polymerase chain reaction (RT-PCR) or t(9;22)(q34;q11) by cytogenetics are not eligible and should be considered for enrollment on studies that incorporate imatinib during induction; please note: patients must also be assessed for CD20 positivity and other markers; positivity for CD22 and CD20 is defined as baseline expression of the CD22 or CD20 antigen in more than 20% of leukemic cells using local multiparameter flow-cytometric immunophenotyping with the use of CD45 expression as a marker to gate the ALL blast population, according to recommendations from the European LeukemiaNet.