Comparing a fracture follow-up service with usual care for osteoporosis
Compares a care-manager follow-up program with usual care in adults with bone fractures.
Key facts
- Who runs it
- National Taiwan University Hospital
- Where
- Taipei, TaiwanSee the site
- Trial code
- Registry title
- Randomized Fracture Liaison Services
- Status
- Enrolling by invitation
- People taking part
- 400 people, planned
- Started
- 23 Jun 2017
- Expected to end
- 31 Dec 2028
- Type of study
- Observational, 2 groups
- Record updated
- 18 May 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people aged 50 or older with a new hip fracture or a newly found spine (vertebral) fracture. It compares a fracture liaison service with usual care.
- Age
- 50 to 100 years
- Sex
- All
- Disease stage
- New hip fracture from the orthopedic ward, or a newly identified vertebral fracture (seen on imaging or causing symptoms), or an old hip fracture with no osteoporosis treatment, referred by team physicians.
- Earlier treatment
- People with an old hip fracture must not have had osteoporosis treatment.
Main reasons for not taking part
- Fractures caused by an injury or by disease (traumatic or pathologic fractures)
- Atypical femoral shaft fracture
- Taking part in other medication trials
- Life expectancy under 2 years, judged by team physicians
- Cannot take part in evaluation because of thinking, communication or physical problems
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- Age>=50
- New hip fracture from orthopedic ward
- Newly identified vertebral fracture (either morphological or clinical)/ old hip fracture without osteoporosis treatment referred by team physicians either inpatients or outpatients
- Willing to accept 10 years of follow-ups
Who cannot take part
- Participating in other medication intervention trials
- Traumatic or pathologic fractures
- Atypical femoral shaft fracture
- Less than 2 years of life expectancy judged by team physicians
- Incapable of accepting evaluation for cognitive, communication, and physical problems judged by team physicians or coordinators
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 100 years old?
Where in Taiwan
- National Taiwan University HospitalTaipei, TaiwanNo longer taking part
About the trial
What the trial wants to find out
Aims: To compare clinical outcomes for patients under FLS and usual care at the NTUH MH and BB.
Read full original descriptionShow less
Method: Four hundred subjects with new hip fracture or newly identified vertebral fracture are randomly assigned into FLS and usual care (UC). FLS subjects received osteoporosis-related assessments, treatments, consultations on diet, medications, exercise, fall preventions given mainly by care managers with followed up telephone call at 4, 8, 12, 18, 24 months then annually for up to 10 years. Care managers will perform baseline assessments and follow them by telephone annually for up to 10 years for UC subjects. Major outcomes include bone mineral density assessment rate, calcium, vitamin D, and osteoporosis medication initiation and adherence rate, fall and fracture incidences, mortality, and healthcare resource utilizations.
The 2 groups in the trial
- FLS
Fracture Liaison Service (Care managers based coordination service for fragility fracture patients with followed up telephone call at 4, 8, 12, 18, 24 months then annually for up to 10 years (to 2028).)
- UC
usual care (Care managers will perform baseline assessments and follow them by telephone annually for up to 10 years (to 2028). )
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Fracture Liaison Service：A Randomized Control Trial
- Plain-language title
- Comparing a fracture follow-up service with usual care for osteoporosisGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT03178799, who can take part
- Record updated
- 18 May 2026