Heat Treatment With Radiation for Advanced Cervical Cancer
Tests heat therapy added to radiation and internal radiation in women with advanced cervical cancer.
Plain-language title generated from the registry record
Registry title: Radiation Therapy or Chemoradiation, Interstitial Brachytherapy in Combination With Hyperthermia in Advanced Cervical Cancer
Key facts
- Where
- Erlangen, GermanySee the site
Where in Germany
- Universitätsklinikum Erlangen, StrahlenklinikErlangen, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Erlangen-Nürnberg Medical School
- Trial code
- NCT03249519
- Record updated
- 15 August 2017
- Original description
The combination of radiation therapy or chemoradiation with Interstitial brachytherapy for advanced cervical cancer (pN+, FIGO-Stage II B - IV A is standard of therapy. The radio- and chemosensitive effect of an additional hyperthermia might improve the clinical outcome.Read full original descriptionShow less
Multimodal Therapy of Advanced Cervical Cancer With Radiotherapy or Chemoradiation, Interstitial Brachytherapy in Combination With Hyperthermia
The combination of radiation therapy or chemoradiation with Interstitial brachytherapy for advanced cervical cancer (pN+, FIGO-Stage II B - IV A is standard of therapy. The radio- and chemosensitive effect of an additional hyperthermia might improve the clinical outcome.
Inclusion: Histological confirmed carcinoma of the Cervix; FIGO-Stage IIB-IVA; earlier stages when inoperable or according to patient's wish; clinical M0; except: involvement of para-aortic lymph nodes; Age ≥ 18 years; ECOG ≤ 2; Informed consent of the patient.
Exclusion: Metal implants (length > 2cm or dense clusters of marker clips in the pelvis); Patients not willing to use effective contraception during and up to 6 months after therapy; Pre-existing uncontrolled cardiac disease, signs of cardiac failure, or rhythm disturbances requiring therapy; Cardiac Pacemaker; Myocardial infarction within the past 12 months; Congestive heart failure; New York Heart Association (NYHA) class III or IV heart disease; Disease that would preclude chemoradiation or deep regional hyperthermia; Active or therapy-resistent bladder infections; Pre-existing or concommitant immunodeficiency Syndrome; Complete bundle branch block; Pregnant or lactating women.