Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
Key facts
- Where
- Calgary, CanadaSee the site
- Phase
- Phase 1/2
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Where in Canada
- University Of CalgaryCalgary, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Calgary
- Trial code
- NCT03255408
- Record updated
- 1 May 2026
- Original description
A prospective double blind, placebo-controlled, randomized cross-over trial to evaluate the effect of lowering cerebral blood flow on the ventilatory chemoreflexes (acute hypoxic and hypercapnic ventilatory responses).Read full original descriptionShow less
Role of Cerebral Blood Flow on Ventilatory Stability During Sleep in Normoxia and Intermittent Hypoxia
A prospective double blind, placebo-controlled, randomized cross-over trial to evaluate the effect of lowering cerebral blood flow on the ventilatory chemoreflexes (acute hypoxic and hypercapnic ventilatory responses).
Inclusion: Healthy adults; 18 - 45 years of age; Living in Calgary for the past one year; Have no medical condition or should not be taking any blood pressure medications; The participant should not be lactose intolerant.
Exclusion: Cerebrovascular, cardio-respiratory, renal and metabolic diseases; Bleeding disorders and upper gastrointestinal diseases e.g. peptic ulcer disease; Drug allergies to non-steroidal anti-inflammatories; Pregnancy, obese and sleep-disordered breathing; Currently smoking.