Liquid Biopsy in Mature B-cell Tumors
Key facts
- Where
- Bellinzona, SwitzerlandSee the site
Where in Switzerland
- Institute of Oncology ResearchBellinzona, SwitzerlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Oncology Institute of Southern Switzerland
- Trial code
- NCT03280394
- Record updated
- 9 July 2026
- Original description
The study aims at assessing whether cell free DNA genotyping can improve the accuracy of early prediction of cure in mature B-cell tumor patients and whether it represents an accessible source of tumor DNA for the sensitive identification of genetic biomarkers that refine the diagnostic workup, stratify prognosis and identify the emergence of drug-resistance mutations during treatment.Read full original descriptionShow less
Prospective, Observational, Multi-centred, Non-interventional Research Project on Plasma Cell Free DNA Genotyping as a Tool to Inform Mature B-cell Tumor Management
The study aims at assessing whether cell free DNA genotyping can improve the accuracy of early prediction of cure in mature B-cell tumor patients and whether it represents an accessible source of tumor DNA for the sensitive identification of genetic biomarkers that refine the diagnostic workup, stratify prognosis and identify the emergence of drug-resistance mutations during treatment.
Inclusion: Male or female adults 18 years or older; Documented diagnosis of mature B-cell tumor according to WHO 2008 criteria; Willing and able to comply with scheduled study procedures; Evidence of a signed informed consent.