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NCT03285230Active, not recruiting

The French E3N Prospective Cohort Study

The French E3N Prospective Cohort Study (Etude Epidémiologique auprès de Femmes de la Mutuelle Générale de l'Education Nationale)

Source: ClinicalTrials.gov · Last updated 25 Jun 2026

Brief summary (registry, in English)

The French E3N cohort was initiated in 1990 to investigate the risk factors associated with cancer and other major non-communicable diseases in women. The participants were insured through a national health system that primarily covered teachers, and were enrolled from 1990 after returning baseline self-administered questionnaires and providing informed consent. The cohort comprised nearly 100 000 women with baseline ages ranging from 40 to 65 years. Follow-up questionnaires were sent approximately every 2-3 years after the baseline and addressed general and lifestyle characteristics together with medical events (cancer, cardiovascular diseases, diabetes, depression, fractures and asthma, among others). The follow-up questionnaire response rate remained stable at approximately 80%. A biological material bank was generated and included blood samples collected from 25 000 women and saliva samples from an additional 47 000 women. Ageing among the E3N cohort provided the opportunity to investigate factors related to agerelated diseases and conditions as well as disease survival.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
100000 (actual)
First submitted
27 Jul 2017
Start date
15 Jun 1990
Primary completion date
15 Nov 1991
Lead sponsor
Institut National de la Santé Et de la Recherche Médicale, France
NCT number
NCT03285230

What you commit to

  • Study type: Observational
  • Participants enrolled: 100000
  • From 15 Jun 1990 to the primary completion date, 15 Nov 1991
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • \- men

Who the study is looking for

  • only women
  • born between 1925 and 1950
  • insured by the Mutuelle Générale de l'Education Nationale (MGEN)

Age in the registry: 40 years to - · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
-
Coordinator of this site? Confirm its status
VillejuifFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.