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Morphologic Evolution and Remodeling of Intracranial Atherosclerosis: A Longitudinal Study by 3D-rotational Angiography

Key facts

Where
Hong Kong, Hong KongSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Source: NCT03295773, who can take part

Where in Hong Kong

  • Chinese University of Hong KongHong Kong, Hong KongTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Chinese University of Hong Kong
Trial code
NCT03295773
Record updated
24 February 2026
Original description
This study is to elucidate the morphologic evolution and remodeling of ICAD under stringent control of cardiovascular risk factors.Read full original descriptionShow less

This study is to elucidate the morphologic evolution and remodeling of ICAD under stringent control of cardiovascular risk factors.

Inclusion: Patient is 30 to 85 years of age, inclusive; Patients who have an acute infarct in diffusion-weighted MRI compatible with artery-to-artery thrombo-embolism and a relevant intracranial atherosclerotic stenosis ≥60%; Patient who has no contra-indication for the proposed imaging tests; Patient understands the purpose and requirements of the study, and has provided an informed consent.

Exclusion: Patient with any of the following conditions would be excluded:; Stroke etiology uncertain or unrelated to intracranial atherosclerosis, such as cardioembolism, Moyamoya disease, small vessel disease or primary angiitis of CNS; A medical condition that would not allow the patient to adhere to the protocol or complete the study; Bleeding propensity: active peptic ulcer disease, major systemic hemorrhage within 30 days, thrombocytopenia (platelets <100 x 109/L), coagulopathy (INR >1.5); A tandem stenosis >50% at extra-cranial internal carotid artery.

ClinicalTrials.gov NCT03295773