PTSD After ICU Survival - Caring for Patients With Traumatic Stress Sequelae Following Intensive Medical Care
Key facts
- Who runs it
- Ludwig-Maximilians - University of Munich
- Where
- Germany2 sites in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 319 people enrolled
- Started
- 21 Oct 2018
- Ended
- 18 Jan 2024
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- "Narrative Exposure Therapy"-oriented intervention
- improved treatment as usual (iTAU)
- Record updated
- 23 April 2025
Who can take part
- Age
- 18 years to 85 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 2 criteriaShow less
Who cannot take part
- GPs:
Other criteria
- Patients:
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
During the PICTURE trial a short narrative therapy (narrative exposure therapy adapted for primary care) for patients with posttraumatic stress disorder (PTSD) after intensive care treatment is to be carried out by their general practitioner (GP). During regular practice hours, this is often difficult. For this reason, we are investigating whether the regular treatment can be improved by a specially trained GP.
Read full original descriptionShow less
The aim of the study is to investigate the effects and applicability of a short version of an established narrative therapy for patients with posttraumatic stress disorders after intensive medical treatment.
Three months after discharge from the intensive care unit, the diagnosis of a PTSD symptoms is verified and the patients are randomized into two groups.
In the treatment group, the physician will perform three 45-minute therapy sessions with the patient within 6 weeks. During the first session a list of the most intense events - both positive and negative - in the life of the patient is drawn on the basis of a life line, with the stay at the intensive care unit being one of these events. The second session deals with the experience during intensive care in detail, led by the GP. During the third session, another event from the patient's life will be discussed in the same manner. This way, the different components (cognitions, emotions, body reactions, context information) can be reconnected and classified into the patient's own biography. Between the therapy sessions, a conversation between the GP and the psychologist will take place to support the GP during the therapy. In order to monitor the patient's safety and compliance, standardized telephone calls between the patient and the GP practice are regularly carried out every 2-3 weeks in between therapy sessions up to the first data collection after 6 months (T1).
In the control group there are three doctor-patient contacts, too, which content is based on the patient's symptoms. This group thus receives the standard therapy which is customary in practice.
The 2 groups in the trial
- Intervention-groupTreatment being tested
Narrative Exposure Therapy (NET): for GP-practice adapted version of narrative exposure therapy during 3 sessions (à 45 minutes)
Treatment: "Narrative Exposure Therapy"-oriented intervention
- iTAU groupExisting treatment, for comparison
Improved Treatment-as-usual: 3 GP consultations with patients according to guidelines and adapted to patients' needs
Treatment: improved treatment as usual (iTAU)
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- PTSD After ICU Survival - Caring for Patients With Traumatic Stress Sequelae Following Intensive Medical Care - a Multi-Center, Observer-blinded, Randomized, Controlled Trial With a Psychological Intervention
- Publications
- Acceptance of a general practitioner-led narrative exposure intervention on post-traumatic stress symptoms after intensive care: a qualitative interview study with providers.BMJ open, 2026
- Effects of a brief primary care intervention for post-traumatic stress disorder symptoms after critical illness on health-related quality of life - A secondary analysis of the PICTURE randomised controlled trial.The European journal of general practice, 2026
- Depressive symptoms are a key determinant of health-related quality of life in ICU survivors with psychological distress.Scientific reports, 2026
- Effects of a general practitioner-led brief narrative exposure intervention on symptoms of post-traumatic stress disorder after intensive care (PICTURE): multicentre, observer blind, randomised controlled trial.BMJ (Clinical research ed.), 2025
- Patient perspectives on stress after ICU and a short primary care based psychological intervention - results from a qualitative sub‑study of the PICTURE trial.BMC primary care, 2025
- Record updated
- 23 April 2025