NCT03349242Completed
Natural History Study of Patients With X-linked Retinal Dystrophy Associated With Mutations in Retinitis Pigmentosa GTPase Regulator (RPGR)
Source: ClinicalTrials.gov · Last updated 20 Jun 2024
Brief summary (registry, in English)
The rod-cone dystrophies (often referred to as retinitis pigmentosa (RP)) are a clinically and genetically heterogeneous group of disorders in which there is progressive loss of rod and later cone photoreceptor function leading to severe visual impairment. RP usually occurs as an isolated retinal disorder, but it may also be seen in association with systemic abnormalities.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 140 (actual)
- First submitted
- 13 Nov 2017
- Start date
- 19 Dec 2017
- Primary completion date
- 19 Apr 2024
- Lead sponsor
- MeiraGTx UK II Ltd
- Diseases
- Retinitis pigmentosa
- NCT number
- NCT03349242
What you commit to
- Study type: Observational
- Participants enrolled: 140
- From 19 Dec 2017 to the primary completion date, 19 Apr 2024
- 8 sites in 3 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Are unable or unwilling to undertake consent or clinical testing
Who the study is looking for
- Males \& Females aged 5 years or older
- Have RPGR-associated retinal dystrophy
- Are able to give informed consent or assent, with the guidance of their parent/guardian where appropriate
- Are able to undertake age-appropriate clinical assessments as specified in the protocol
- Have genetic mutation within the RPGR gene confirmed by an accredited lab or research lab.
Age in the registry: 5 years to - · Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Hospital for Sick Children Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
| Moorfields Eye Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Kellogg Eye Center Coordinator of this site? Confirm its status | Ann Arbor | United States | Unknown status |
| Emory Eye Centre Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
| Massachusetts Eye and Ear Infirmary Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Shiley Eye Institute - UCSD Coordinator of this site? Confirm its status | La Jolla | United States | Unknown status |
| UPMC Eye Centre Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
| Stanford University, Spencer Center for Vision Research Coordinator of this site? Confirm its status | Stanford | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.