Studies movement and brain activity in people with Parkinson disease
Compares movement adaptation and brain electrical activity in adults with Parkinson disease.
Key facts
- Who runs it
- Assistance Publique Hopitaux De Marseille
- Where
- Marseille, FranceSee the site
- Trial code
- Registry title
- Movement Error-processes and Sensorimotor Adaptation in Parkinsonian Patient
- Status
- Recruiting
- People taking part
- 100 people, planned
- Started
- 4 Jul 2019
- Expected to end
- Oct 2027
- Type of study
- Observational, 3 groups
- Treatments tested
- Assessment of behavioral performance and the electrophysiological (EEG) activity in PD patients during the early and more advanced stages of the pathology
- Record updated
- 5 January 2024
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for right-handed adults with Parkinson's disease who already have stimulation electrodes in both subthalamic nuclei.
- Age
- Over 18 years
- Sex
- Men and women can join.
- Disease stage
- Idiopathic Parkinson's disease with a history of more than 5 years, diagnosed by Gibb criteria. Dopa-sensitivity greater than 50%.
- Earlier treatment
- Stimulation electrodes implanted in the 2 subthalamic nuclei at La Timone Hospital.
Main reasons for not taking part
- Signs of cognitive impairment
- Pregnant or likely to be pregnant during the year
- Cannot give informed consent, or cannot understand the study
- Cannot read or write French
- Cannot take part in an MRI study
The registry criteria, word for word
Show all 16 criteriaShow less
Who can take part
- Patient aged over 18 years
- Right-handed patients , following the Modified Edinburgh Handedness Inventory
- Patient with Parkinson's disease according to Gibb criteria
- Idiopathic Parkinson's Disease with a history of more than 5 years
- Stimulation electrodes implanted in the 2 subthalamic nuclei in the Functional and Stereotactic Neurosurgery Department of La Timone Hospital (Pr REGIS)
- Dopa-sensitivity greater than 50%
- Absence of signs of cognitive impairment
- Patient who agreed to participate in the study and signed informed consent
- Patient affiliated with a health insurance
Who cannot take part
- Person not likely to participate in the entire study
- Pregnant or likely to be pregnant during the year
- Patients unable to give their informed consent (detainees, adults under guardianship)
- Person unable to understand the nature and purpose of the study, or presneting with understanding difficulties which could compromise the proper conduct of the study
- Person refusing to sign the Informed Consent Form
- A person who is able to give his or her consent but unable to read / write French language
- patient who can not participate in an MRI study according to the criteria listed in the attached form
Where in France
- Service de Neurologie, Hôpital de la Timone, Assistance Publique Hôpitaux de MarseilleMarseille, FranceContact: Alexandre Eusebio, MD, PhDTaking people
About the trial
What the trial wants to find out
The aim of the present project is to document the relationship between the behavioral deficits and the electrophysiological anomalies observed in PD patients in tasks involving motor adaptation to visual or mechanical perturbations.
The 3 groups in the trial
- Parkinsonian patient under dopaminergic medication
Treatment: Assessment of behavioral performance and the electrophysiological (EEG) activity in PD patients during the early and more advanced stages of the pathology
- Parkinsonian patient without dopaminergic medication
Treatment: Assessment of behavioral performance and the electrophysiological (EEG) activity in PD patients during the early and more advanced stages of the pathology
- Control participants
Treatment: Assessment of behavioral performance and the electrophysiological (EEG) activity in PD patients during the early and more advanced stages of the pathology
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Movement Error-processes and Sensorimotor Adaptation in Parkinsonian Patient
- Plain-language title
- Studies movement and brain activity in people with Parkinson diseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 5 January 2024