NCT03402919Recruiting
Comprehensive Assessment of Neurodegeneration and Dementia
The Comprehensive Assessment of Neurodegeneration and Dementia Study
Source: ClinicalTrials.gov · Last updated 20 Jan 2026
Brief summary (registry, in English)
This is a longitudinal observational study recruiting individuals between the ages of 50 and 90 with different types of dementia as well as a comparison group without cognitive deficits. Participants are/will be recruited at sites across Canada and will undergo assessments, neuroimaging, and biological sample collection.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1573 (estimated)
- First submitted
- 11 Jan 2018
- Start date
- 1 Jun 2016
- Primary completion date
- 30 Nov 2023
- Lead sponsor
- McGill University
- NCT number
- NCT03402919
What you commit to
- Study type: Observational
- Planned participants: 1573
- From 1 Jun 2016 to the primary completion date, 30 Nov 2023
- 19 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- The presence of other significant known chronic brain disease such as: moderate to severe chronic static leukoencephalopathy (including previous traumatic injury), multiple sclerosis, a serious developmental handicap, malignant tumors, Parkinson's disease (other than for the Parkinson's cohort), and other rarer brain illnesses
- Ongoing alcohol or drug abuse which in the opinion of the investigator may interfere with the subject's ability to comply with the study procedures
- Symptomatic stroke within the previous year
Other
- Unable to undergo MRI scan due to medical contraindications or inability to tolerate the procedure
Who the study is looking for
- Has subjective or objective cognitive impairment
- Written informed consent must be obtained and documented (from the patient or, where jurisdictions allow it, from a caregiver/family member)
- Sufficient proficiency in English or French to undertake self report and neuropsychological testing
- Geographic accessibility to the study site
- Must have a study partner who can participate as required in the protocol (provide corroborative information)
- Up to 12 years of education
- Fits into one of the following groups: Cognitively Unimpaired, Subjective Cognitive Impairment, Mild Cognitive Impairment, Vascular Mild Cognitive Impairment, Parkinson's Disease, Parkinson's Disease with Mild Cognitive Impairment
Age in the registry: 50 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (19)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Of Calgary Coordinator of this site? Confirm its status | Calgary | Canada | Recruiting |
| University of Alberta Hospital Coordinator of this site? Confirm its status | Edmonton | Canada | Recruiting |
| Veteran's Memorial Building Coordinator of this site? Confirm its status | Halifax | Canada | Recruiting |
| Hamilton General Hospital Coordinator of this site? Confirm its status | Hamilton | Canada | Recruiting |
| Gait and Brain Lab Coordinator of this site? Confirm its status | London | Canada | Recruiting |
| St. Joseph's Health Care London Coordinator of this site? Confirm its status | London | Canada | Recruiting |
| Jewish General Hospital/McGill Memory Clinic Coordinator of this site? Confirm its status | Montreal | Canada | Recruiting |
| Clinique de cognition Institut universitaire de gériatrie de Montréal Coordinator of this site? Confirm its status | Montreal | Canada | Recruiting |
| Research Institute of the McGill University Health Centre Coordinator of this site? Confirm its status | Montreal | Canada | Active, not recruiting |
| Bruyère Research Institute Coordinator of this site? Confirm its status | Ottawa | Canada | Active, not recruiting |
| Kawartha Centre Coordinator of this site? Confirm its status | Peterborough | Canada | Active, not recruiting |
| Hôpital Enfant-Jésus Coordinator of this site? Confirm its status | Québec | Canada | Recruiting |
| Centre de recherche sur le vieillissement CIUSSS de l'Estrie-CHUS Coordinator of this site? Confirm its status | Sherbrooke | Canada | Active, not recruiting |
| University Health Network Memory Clinic Coordinator of this site? Confirm its status | Toronto | Canada | Active, not recruiting |
| Sunnybrook Health Sciences Centre Coordinator of this site? Confirm its status | Toronto | Canada | Active, not recruiting |
| Baycrest Clinical Unit Coordinator of this site? Confirm its status | Toronto | Canada | Recruiting |
| Djavad Mowafaghian Centre for Brain Health Coordinator of this site? Confirm its status | Vancouver | Canada | Recruiting |
| Island Health Coordinator of this site? Confirm its status | Victoria | Canada | Not yet recruiting |
| University of Waterloo Coordinator of this site? Confirm its status | Waterloo | Canada | Active, not recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.