Collects samples from people with gynecologic cancer for biomarker research
Collects blood, tumour tissue and fluid from adults with gynecologic cancer for research.
Plain-language title generated from the registry record
Registry title: Study Looking at Biomarkers in Ovarian Cancer
Key facts
- Where
- Barrie, Hamilton, Kingston, London, Ottawa, and Toronto, CanadaSee the 7 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women with stage III or IV high grade serous ovarian, tubal or primary peritoneal cancer. Samples of blood, tumour tissue and fluids are collected for biomarker research.
- Age
- 18 years or older
- Sex
- Women only
- Disease stage
- Stage III or IV high grade serous ovarian, tubal or primary peritoneal cancer. ECOG Performance Status 0-1. Life expectancy of 6 months or more.
- Biomarker or test result
- No specific biomarker is required to join. The trial collects samples to study biomarkers.
Main reasons for not taking part
- Early stage (I and II) high grade serous, tubal or primary peritoneal cancer
- A tumour type other than high grade serous
- A medical reason that rules out a tumour biopsy or blood sampling
Read by machine on 12 November 2026.
Where in Canada
- Royal Victoria Regional Health CentreBarrie, CanadaContact: Leah Jutzi, MDTaking people
- Juravinski Cancer CentreHamilton, CanadaContact: Amit Oza, M.D.No longer taking part
- Kingston Health Sciences CentreKingston, CanadaContact: Josee-Lyne Ethier, M.D.Taking people
- London Health Sciences CentreLondon, CanadaContact: Stephen Welch, MDTaking people
- The Ottawa Hospital Cancer CentreOttawa, CanadaContact: Johanne Weberpals, M.D.Taking people
- Princess Margaret Cancer CentreToronto, CanadaContact: Amit Oza, M.D.Taking people
- Sunnybrook Health Sciences CentreToronto, CanadaContact: Helen MacKay, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University Health Network, Toronto
- Trial code
- NCT03419689
- Record updated
- 4 December 2025
- Original description
This is a sample study that will collect biological samples (blood, tumor tissue, ascites, and/or other fluids) from gynecological cancer patients for biomarker research. In addition, the results of the testing done on the samples will be given to the participant's treating physician who may use the information to guide treatment decisions.Read full original descriptionShow less
Biomarker Discovery Project in High Grade Serous Ovarian Cancer
This is a sample study that will collect biological samples (blood, tumor tissue, ascites, and/or other fluids) from gynecological cancer patients for biomarker research. In addition, the results of the testing done on the samples will be given to the participant's treating physician who may use the information to guide treatment decisions.
Inclusion: Histological diagnosis of stage III or IV high grade serous ovarian, tubal or primary peritoneal cancer; Must be 18 years of age or older; Eastern Cooperative Oncology Group (ECOG) Performance Status 0-1; Have a life expectancy greater than or equal to 6 months; Able to provide adequate informed consent; Willing to undergo blood or fluid collection and tumour biopsy; Patients enrolled at the time of surgery must agree to have part of their tumour used for the purpose of the study; Archival tissue must be available for patients that are enrolled at the time of progression.
Exclusion: Must not have early stage (I and II) high grade serous, tubal or primary peritoneal cancer; Must not have other tumour histology other than high grade serous; Must not have contraindication to tumour biopsy and/or blood sampling.