Assessment of Stroke Volume and Cardiac Output in Response to Varying Heart Rates
Key facts
- Where
- Calgary, CanadaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Where in Canada
- University Of CalgaryCalgary, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Calgary
- Trial code
- NCT03446326
- Record updated
- 5 May 2026
- Original description
The investigators will seek to determine the effects of different heart rates on both stroke volume and cardiac output using non-invasive hemodynamic assessments. In order to safely manipulate the HR, the investigators will study patients with permanent pacemakers in whom heart rate manipulation can be done in a safe and non-invasive manner.Read full original descriptionShow less
Assessment of Stroke Volume and Cardiac Output in Response to Varying Heart Rates and Body Position - a Pacemaker Based Study
The investigators will seek to determine the effects of different heart rates on both stroke volume and cardiac output using non-invasive hemodynamic assessments. In order to safely manipulate the HR, the investigators will study patients with permanent pacemakers in whom heart rate manipulation can be done in a safe and non-invasive manner.
Inclusion: Age 18-70 years (inclusive); Implanted permanent pacemaker or implanted defibrillator capable of atrial and ventricular pacing; LV ejection fraction >50%.
Exclusion: Clinical need for a cardiac resynchronization device; Unable or unwilling to provide informed consent.