Tests a limb blood pressure device during helicopter transport for stroke
Tests a limb blood pressure device in adults with acute stroke during helicopter transport.
Plain-language title generated from the registry record
Registry title: Ischemic Conditioning During Air tRansport Save penUmbral Tissue
Key facts
- Where
- Iowa City, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT03481205, who can take part
Where in United States
- University of IowaIowa City, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Enrique Leira
- Trial code
- NCT03481205
- Record updated
- 10 November 2025
- Original description
The purpose of this study is to demonstrate the feasibility of performing remote limb ischemic conditioning (RLIC) using the Doctormate device, a special blood pressure device used to perform RLIC, on patients with acute ischemic stroke due to large vessel occlusion being transported to a thrombectomy capable center by the helicopter.Read full original descriptionShow less
Ischemic Conditioning During Air tRansport Save penUmbral Tissue
The purpose of this study is to demonstrate the feasibility of performing remote limb ischemic conditioning (RLIC) using the Doctormate device, a special blood pressure device used to perform RLIC, on patients with acute ischemic stroke due to large vessel occlusion being transported to a thrombectomy capable center by the helicopter.
Inclusion: Age ≥18 and ≤ 80 years; Suspected acute ischemic stroke with symptoms suggestive of large vessel occlusion (aphasia, agnosia, neglect, visual field cut, and gaze preference); Patient screened for rtPA, and rtPA administered if eligible; Subject or legally authorized representative able to provide consent at the time of the assessment; NIHSS 6-20.
Exclusion: Any intracranial hemorrhage (parenchymal, subarachnoid, subdural, epidural) on CT scan at the community hospital; History of upper or lower extremity ischemia, known subclavian, brachial artery, iliac or femoral artery stenosis, subclavian steal syndrome, any upper or lower extremity soft tissue, orthopedic or vascular injury, or mastectomy or other procedure that may contraindicate taking blood pressure or having a cuff on the arm or leg for the conditioning treatment; History of diabetes mellitus; Arteriovenous fistula in upper limb; Pregnancy. Patients ages 18-55 will need to have a negative urine or blood based pregnancy test; Enrollment in another clinical trial; Patient incarcerated; Agitation deemed unsafe for ischemic preconditioning testing.