Tests whether exercise training improves blood vessel function in type 1 diabetes
Tests exercise training against usual life in adults with type 1 diabetes.
Plain-language title generated from the registry record
Registry title: Exercise Training and Endothelial Function in Type 1 Diabetes
Key facts
- Where
- Lille, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 50 years old?
Source: NCT03528226, who can take part
Where in France
- Hop Claude Huriez Chu LilleLille, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Lille
- Trial code
- NCT03528226
- Record updated
- 14 May 2026
- Original description
Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T1D). In a preventive setting, in T1D patients still free of complications, the research of non-pharmacological interventions to improve endothelial function appears fundamental.Read full original descriptionShow less
Impact of Exercise Training on Endothelial Function in Adults With Type 1 Diabetes
Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T1D). In a preventive setting, in T1D patients still free of complications, the research of non-pharmacological interventions to improve endothelial function appears fundamental.
In this randomized controlled trial, the effects of exercise training on endothelial function will be evaluated in T1D adults. Secondary objectives are to evaluate the exercise training effects on the micro and macrovascular function and exercise-induced tissue vasoreactivity and their possible neurometabolic consequences.
An improvement in vascular function, particularly endothelium-dependent, as well as in neurometabolic profile, through this non-pharmacological strategy is expected
Inclusion: Covered by social security; With a T1Diabete, diagnosed for at least 1 year, and free from macrovascular and microvascular diabetic complications.
Exclusion: type 1 diabetes diagnoses for less than 1 year; MODY diabetes, mitochondrial diabetes or type 2 diabetes; Hypertension; Active chronic disease or in remission (excluding type 1 diabetes); presence of macrovascular and/or microvascular diabetic complications (retinopathy, nephropathy, neuropathy ,…); Obesity (Body Mass Index > 30 kg/m²; Smokers; Disabling painful discomfort for trunk, upper or lower limb movements; Head trauma in the past.