Tests whether exercise training improves blood vessel function in type 1 diabetes
Tests exercise training against usual life in adults with type 1 diabetes.
Key facts
- Who runs it
- University Hospital, Lille
- Where
- Lille, FranceSee the site
- Trial code
- Registry title
- Exercise Training and Endothelial Function in Type 1 Diabetes
- Status
- Recruiting
- People taking part
- 34 people, planned
- Started
- 12 Nov 2019
- Expected to end
- Nov 2028
- Type of study
- Interventional, 2 groups
- Treatments tested
- Exercise Training Procedure
- Normal life procedure
- Record updated
- 14 May 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with type 1 diabetes for at least 1 year who have no diabetes complications. It tests whether exercise training improves blood vessel function.
- Age
- 18 Years to 50 Years
- Sex
- All sexes can join.
- Disease stage
- Type 1 diabetes diagnosed for at least 1 year, with no macrovascular or microvascular diabetic complications.
Main reasons for not taking part
- Type 1 diabetes for less than 1 year
- MODY diabetes, mitochondrial diabetes or type 2 diabetes
- Diabetic complications such as retinopathy, nephropathy or neuropathy
- Obesity (Body Mass Index > 30 kg/m²)
- Smokers or people with hypertension
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- Covered by social security
- With a T1Diabete, diagnosed for at least 1 year, and free from macrovascular and microvascular diabetic complications
Who cannot take part
- type 1 diabetes diagnoses for less than 1 year
- MODY diabetes, mitochondrial diabetes or type 2 diabetes
- Hypertension
- Active chronic disease or in remission (excluding type 1 diabetes)
- presence of macrovascular and/or microvascular diabetic complications (retinopathy, nephropathy, neuropathy ,…)
- Obesity (Body Mass Index > 30 kg/m²
- Smokers
- Disabling painful discomfort for trunk, upper or lower limb movements
- Head trauma in the past
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 50 years old?
Where in France
- Hop Claude Huriez Chu LilleLille, FranceContact: Anne Vambergue, MD,PhDTaking people
About the trial
What the trial wants to find out
Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T1D). In a preventive setting, in T1D patients still free of complications, the research of non-pharmacological interventions to improve endothelial function appears fundamental.
Read full original descriptionShow less
In this randomized controlled trial, the effects of exercise training on endothelial function will be evaluated in T1D adults. Secondary objectives are to evaluate the exercise training effects on the micro and macrovascular function and exercise-induced tissue vasoreactivity and their possible neurometabolic consequences.
An improvement in vascular function, particularly endothelium-dependent, as well as in neurometabolic profile, through this non-pharmacological strategy is expected
The 2 groups in the trial
- Exercise TrainingTreatment being tested
Treatment: Exercise Training Procedure
- ControlOther group
Treatment: Normal life procedure
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Impact of Exercise Training on Endothelial Function in Adults With Type 1 Diabetes
- Plain-language title
- Tests whether exercise training improves blood vessel function in type 1 diabetesGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT03528226, who can take part
- Record updated
- 14 May 2026