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CompletedNo phase

Ablation at Virtual-hEart pRedicted Targets for VT

Key facts

Who runs it
Johns Hopkins University
Where
Baltimore, United StatesSee the site
Trial code
Status
Completed
People taking part
10 people enrolled
Started
26 Sept 2022
Ended
1 Dec 2025
Type of study
Interventional
Treatments tested
  • Virtual Heart Guided Ablation
Record updated
5 February 2026

Who can take part

Age
18 years and older
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 8 criteriaShow less

Who can take part

  • Eligible patients must be at least 18 years old at the time of enrollment
  • A Pre-Op cardiac MRI including late gadolinium enhancement (LGE) must be performed prior to ablation. As Johns Hopkins University (JHU) performs MRIs with implantable cardioverter defibrillator (ICD) or pacemaker implanted, patients with these devices may be enrolled
  • Eligible patients must suffer from VT, thought to be secondary to structural heart disease (scarring)
  • Eligible patients must be determined to be suitable candidates for ablation to treat VT by their cardiologist and/or electrophysiologists regardless of this protocol

Who cannot take part

  • Patients with Glomerular Filtration Rate (GFR) < 30 mL/min should not be enrolled in the study due to the use of intravenous gadolinium as an MRI contrast agent
  • If a pre-procedure MRI cannot or likely will not be performed for any reason (such as claustrophobia), the patient must be excluded
  • Pregnant women may not participate in the study because gadolinium MRI contrast is contraindicated in these patients
  • Any subject that, during the course of the pre-procedure imaging, is discovered to have VT not related to scarring, he/she must be de-enrolled from the study

Where in United States

  • Johns HopkinsBaltimore, United StatesNo longer taking part

About the trial

What the trial wants to find out

The goal of this study is to test the efficacy of the new imaging/simulation ("virtual heart") approach for determining the optimal ablation sites in patients with VT, which render post-infarction VT non-inducible. The study will test both the acute outcome of the ablation procedure, and the effect the use of the predicted targets has upon procedure time.

The group in the trial

  • Virtual Heart Guided AblationTreatment being tested

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Record updated
5 February 2026