Following People With Lacunar Stroke to Track Thinking and Daily Abilities
Follows adults with a recent small-vessel stroke to observe changes in thinking and disability.
Plain-language title generated from the registry record
Registry title: Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar Infarcts
Key facts
- Where
- Paris, FranceSee the site
Where in France
- Hôpital LariboisièreParis, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Assistance Publique - Hôpitaux de Paris
- Trial code
- NCT03552926
- Record updated
- 2 May 2022
- Original description
The aim of this study is to determine in patients with a recent lacunar strokes (<15 days), the natural history of cognitive disturbances and disability.Read full original descriptionShow less
Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar Infarcts at Lariboisière Fernand-Widal and Sainte Anne Hospitals
The aim of this study is to determine in patients with a recent lacunar strokes (<15 days), the natural history of cognitive disturbances and disability.
Inclusion: Age 18 years and above; History of recent (less than 15 days) neurological deficit related to a small subcortical infarct (evidenced by medical history or physical examination); Diagnosis of recent small subcortical infarct on MRI (hyperintensity on diffusion-weighted imaging showing an infarction in the territory of one perforating artery) presumably responsible for the corresponding neurological deficit; Lesion diameter mess than 20 mm; Ability to comply with scheduled follow-up and annual neurological evaluation; Affiliation to the national French health insurance (sécurité sociale); Signature of informed consent.
Exclusion: Prior diagnosis of dementia according to DSM IV criteria; Prior severe disability with Rankin scale ≥ 4; Serious concomitant systemic disorder that can compromise the follow-up study; Severe psychiatric disorder; Leukoencephalopathy of non-vascular origin; Inability to obtain an informed signed consent from the patient or his/her family; Medical contraindication or refusal to undergo cerebral magnetic resonance scanning (MRI).