Follows older Shenzhen residents to study causes of chronic disease
Follows residents aged 65 or older to study heart and metabolic disease causes.
Plain-language title generated from the registry record
Registry title: Nanshan Elderly Cohort Study
Key facts
- Where
- Guangzhou and Shenzhen, ChinaSee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for apparently healthy older adults, aged 65 or over, who are Chinese and have lived in Nanshan, Shenzhen for at least 5 years.
- Age
- 65 years or older
- Sex
- Women and men can join.
- Disease stage
- Apparently healthy residents, with no hospital-confirmed diabetes, heart, liver or kidney failure, cancer or cardiovascular events.
Main reasons for not taking part
- History of hospital-confirmed diabetes, failure of the heart, liver or kidney, cancer, or cardiovascular disease events
- On a special diet because of a disease or weight control
- Mental or physical disability
- Likely to move to another city within 5 years
- Not willing to take part in every survey item or sample collection
Read by machine on 9 November 2026.
Where in China
- Department of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen UniversityGuangzhou, ChinaNo longer taking part
- Department of Non-communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease ControlShenzhen, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sun Yat-sen University
- Trial code
- NCT03569735
- Record updated
- 26 June 2018
- Original description
Objective: The Nanshan Elderly Cohort Study (NECS) aims to investigate the nutritional, as well as other environmental and genetic factors of chronic diseases, such as cardio-metabolic diseases.Read full original descriptionShow less
Nanshan Elderly Cohort Study：a Community-based Prospective Cohort Study in Nanshan， Shenzhen Residents
Objective: The Nanshan Elderly Cohort Study (NECS) aims to investigate the nutritional, as well as other environmental and genetic factors of chronic diseases, such as cardio-metabolic diseases.
Study design: NECS is a community-based prospective cohort study. Participants: About 10000-20000 apparently healthy residents, living in Nanshan， Shenzhen (South China) for >5 years, aged ≥ 65 years, will be recruited between 2018 and 2019.
Visits and Data Collection: Participants will be followed up approximately every 3 years by invited to the Community Healthcare Service Centre. At each survey, face-to-face interviews, anthropometric measurements, ultrasonography examination, electrocardiogram test and specimen collection will be conducted.
Key variables:
1. Face-to-face interviews: Structured questionnaires will be used to collect the participants' socio-demographic characteristics, lifestyles, habitual dietary intake, physical activity, history of chronic diseases, use of supplements and medications, family history, psychological health and cognitive function. 2. Physical examinations: Anthropometric measurements, blood pressure tests, handgrip strength, and usual gait speed. 3. Ultrasonography examinations: Ultrasonography examination will be performed to determine carotid artery intima-media thickness and plaque, fatty liver. 4. Electrocardiogram test: Electrocardiogram test is to obtain information about the structure and function of the heart. 5. Specimen collections: Overnight fasting blood sample, early morning first-void urine sample and faeces samples will be collected and stored at -80°C till tests. 6. Laboratory tests:
1. Blood tests: Metabolic syndrome-related indices; nutritional indices; inflammatory markers; sexual hormones; genetic markers. 2. Urinary tests: Flavonoids and flavones, minerals, creatinine and renal function related markers. 3. Fecal test: Gut microbiota and related metabolites. 7. Morbidity and mortality: Relevant data will be also retrieved via local multiple Health information systems. 8. Others: Many other laboratory tests or instrument tests will be developed depended on needs and resources in future.
Inclusion: Age: ≥ 65 years; Living in Nanshan, Shenzhen for at least 5 years; Chinese.
Exclusion: Had a history of hospital-confirmed diabetes, failure(s) of heart, liver, or kidney, cancer, CVD events; On special diet due to a disease or weight control; Mental and physical disability; Likely to move to other city within 5 years; Did not want to attend any one item of the survey or sample collection.