Follows older Shenzhen residents to study causes of chronic disease
Follows residents aged 65 or older to study heart and metabolic disease causes.
Plain-language title generated from the registry record
Registry title: Nanshan Elderly Cohort Study
Key facts
- Where
- Guangzhou and Shenzhen, ChinaSee the 2 sites
Where in China
- Department of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen UniversityGuangzhou, ChinaNo longer taking part
- Department of Non-communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease ControlShenzhen, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sun Yat-sen University
- Trial code
- NCT03569735
- Record updated
- 26 June 2018
- Original description
Objective: The Nanshan Elderly Cohort Study (NECS) aims to investigate the nutritional, as well as other environmental and genetic factors of chronic diseases, such as cardio-metabolic diseases.Read full original descriptionShow less
Nanshan Elderly Cohort Study：a Community-based Prospective Cohort Study in Nanshan， Shenzhen Residents
Objective: The Nanshan Elderly Cohort Study (NECS) aims to investigate the nutritional, as well as other environmental and genetic factors of chronic diseases, such as cardio-metabolic diseases.
Study design: NECS is a community-based prospective cohort study. Participants: About 10000-20000 apparently healthy residents, living in Nanshan， Shenzhen (South China) for >5 years, aged ≥ 65 years, will be recruited between 2018 and 2019.
Visits and Data Collection: Participants will be followed up approximately every 3 years by invited to the Community Healthcare Service Centre. At each survey, face-to-face interviews, anthropometric measurements, ultrasonography examination, electrocardiogram test and specimen collection will be conducted.
Key variables:
1. Face-to-face interviews: Structured questionnaires will be used to collect the participants' socio-demographic characteristics, lifestyles, habitual dietary intake, physical activity, history of chronic diseases, use of supplements and medications, family history, psychological health and cognitive function. 2. Physical examinations: Anthropometric measurements, blood pressure tests, handgrip strength, and usual gait speed. 3. Ultrasonography examinations: Ultrasonography examination will be performed to determine carotid artery intima-media thickness and plaque, fatty liver. 4. Electrocardiogram test: Electrocardiogram test is to obtain information about the structure and function of the heart. 5. Specimen collections: Overnight fasting blood sample, early morning first-void urine sample and faeces samples will be collected and stored at -80°C till tests. 6. Laboratory tests:
1. Blood tests: Metabolic syndrome-related indices; nutritional indices; inflammatory markers; sexual hormones; genetic markers. 2. Urinary tests: Flavonoids and flavones, minerals, creatinine and renal function related markers. 3. Fecal test: Gut microbiota and related metabolites. 7. Morbidity and mortality: Relevant data will be also retrieved via local multiple Health information systems. 8. Others: Many other laboratory tests or instrument tests will be developed depended on needs and resources in future.
Inclusion: Age: ≥ 65 years; Living in Nanshan, Shenzhen for at least 5 years; Chinese.
Exclusion: Had a history of hospital-confirmed diabetes, failure(s) of heart, liver, or kidney, cancer, CVD events; On special diet due to a disease or weight control; Mental and physical disability; Likely to move to other city within 5 years; Did not want to attend any one item of the survey or sample collection.