NCT03581695Completed
Inflammatory Biomarkers of Pediatric Pulmonary Hypertension
Inflammatory Biomarkers of Pediatric Pulmonary Hypertension: a Prospective Cohort Study
Source: ClinicalTrials.gov · Last updated 4 May 2026
Brief summary (registry, in English)
To investigate if the inflammatory protein, high mobility group box 1 (HMGB1), along with other inflammatory mediators, is elevated in pediatric patients with congenital heart disease (CHD) and pulmonary hypertension as compared to those with CHD alone, or with healthy controls.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 74 (actual)
- First submitted
- 20 Jun 2018
- Start date
- 20 Jun 2018
- Primary completion date
- 11 May 2022
- Lead sponsor
- The Hospital for Sick Children
- NCT number
- NCT03581695
What you commit to
- Study type: Observational
- Participants enrolled: 74
- From 20 Jun 2018 to the primary completion date, 11 May 2022
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- prior bone marrow transplant
- prior solid organ transplant
Other illness
- active systemic infection
- current active cancer
- active cancer treatment
Who the study is looking for
- -patients of any age with congenital cardiac disease coming for catheterization of the right heart, or both the right and left heart.
Age in the registry: 1 day to 18 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital for Sick Children Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.