MRI Scans to Guide Radiation for Liver or Pancreatic Cancer
Checks whether MRI scans can guide radiation in adults with liver or pancreatic cancer.
Plain-language title generated from the registry record
Registry title: MR Guidance for Liver and Pancreas
Key facts
- Where
- Toronto, CanadaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with locally advanced pancreatic cancer or liver cancer (hepatocellular carcinoma) who are planned for radiation treatment. It tests whether MRI scans before each session are practical.
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Locally advanced pancreatic cancer or hepatocellular carcinoma, being considered for chemoradiation, long course radiation therapy, or SBRT. The treatment may aim to remove all of the disease or to ease symptoms. It must be planned for 5 or more radiation sessions.
Main reasons for not taking part
- Ferromagnetic prosthesis
- Pacemaker or implanted defibrillator
- Claustrophobia (fear of enclosed spaces)
Read by machine on 9 November 2026.
Where in Canada
- University Health Network - Princess Margaret Cancer CentreToronto, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Health Network, Toronto
- Trial code
- NCT03582189
- Record updated
- 5 March 2026
- Original description
This is a single centre, single arm, prospective feasibility study that aims to see whether magnetic resonance imaging (MRI) as a source of image guidance before each radiation treatment fraction is feasible, and also if it may provide information that could potentially be used during the treatment to improve the radiation treatment plan.Read full original descriptionShow less
A Feasibility Study of Magnetic Resonance Imaging (MRI) as a Platform for Image Guidance and Adaptive Radiation Therapy in Patients With Liver or Pancreatic Cancer
This is a single centre, single arm, prospective feasibility study that aims to see whether magnetic resonance imaging (MRI) as a source of image guidance before each radiation treatment fraction is feasible, and also if it may provide information that could potentially be used during the treatment to improve the radiation treatment plan.
Patients will have 5 MRIs with each of their RT sessions. If patients' RT treatment will consist of more than 5 fractions, only 5 MRIs will be done with any 5 RT fractions. Patients will be completing a short questionnaire at the end of each MRI. A patient questionnaire will also be completed at the end of the study to assess for patient satisfaction.
There will be 30 evaluable patients enrolled to the study.
Inclusion: Patients 18 years or older; Diagnosed with locally advanced pancreatic cancer or hepatocellular carcinoma being considered for treatment with chemoradiation, long course RT, or SBRT with curative intent or palliative intent, planned for 5 or more RT fractions.
Exclusion: Contraindications for MRI: ferromagnetic prosthesis, pacemaker / implanted defibrillator, claustrophobia.