Fasting Mimicking Diet Tested in Adults With Mild to Moderate Ulcerative Colitis
Tests a fasting-mimicking diet to see its effect on inflammation in adults with colitis.
Plain-language title generated from the registry record
Registry title: The Influence of a Fasting Mimicking Diet on Ulcerative Colitis
Key facts
- Where
- Palo Alto, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT03615690, who can take part
Where in United States
- Stanford UniversityPalo Alto, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Stanford University
- Trial code
- NCT03615690
- Record updated
- 27 February 2026
- Original description
The purpose of this study is to see how a diet that mimics fasting effects inflammation in patients with mild to moderate Ulcerative Colitis (UC). The diet may allow users to receive the benefits of fasting while also being able to enjoy food (the ingredients of which are GRAS (generally recognized as safe) by the Food and Drug Administration (FDA). Research on dietary interventions and UC are very limited. Fasting mimicking diets (FMD) have been studied with support of the National Institute of Health and published in leading journals. This research investigates whether markers of inflammation decrease and/or quality of life increases after three cycles of a five-day period of the fasting mimicking diet, and may provide rationale for its use to treat UC.Read full original descriptionShow less
The Influence of a Fasting Mimicking Diet on Ulcerative Colitis
The purpose of this study is to see how a diet that mimics fasting effects inflammation in patients with mild to moderate Ulcerative Colitis (UC). The diet may allow users to receive the benefits of fasting while also being able to enjoy food (the ingredients of which are GRAS (generally recognized as safe) by the Food and Drug Administration (FDA). Research on dietary interventions and UC are very limited. Fasting mimicking diets (FMD) have been studied with support of the National Institute of Health and published in leading journals. This research investigates whether markers of inflammation decrease and/or quality of life increases after three cycles of a five-day period of the fasting mimicking diet, and may provide rationale for its use to treat UC.
Inclusion: Mild to moderate Ulcerative Colitis on the partial Mayo Score out of 9 (score between 2 to 7); Age of 18-70 at start of study (inclusive).
Exclusion: Individuals who are taking medication which may not be safely consumed with a calorie restricted diet; Patients with relevant prior gastrointestinal surgery and consequences such as short bowel syndrome, ostomy of small or large intestine, hemi- or total colectomy, proctocolectomy, ileoanal pouch will be excluded; Individuals allergic to nuts; Individuals diagnosed with a serious medical condition as defined by the patient's physician, unless approved in writing by a physician; Individuals who have been severely weakened by a disease or medical procedure,; Individuals with diabetes who are taking anti-diabetic drugs associated with risk of hypoglycemia; Individuals with more than mild-moderate cardiovascular disease or life-threatening cancer (as determined by patient's physician) unless approved by a physician; Individuals with a history of syncope; Individuals with history of severe cardiac disease (particularly uncompensated congestive heart failure NYHA grade 2 or more or LVEF < 40%); Individuals with liver or kidney disorders that may be affected by very low glucose and protein content of the diet; Women who are pregnant or nursing or expect to be pregnant; Individuals with a body mass index (BMI) lower than 18; Individuals with dietary needs incompatible with the FMD meal plan; Patients on a caloric restricted diet will also be excluded.