Studying how grandmothers' health may affect their children and grandchildren
Follows women in Guangzhou, China, and their children and grandchildren over time.
Plain-language title generated from the registry record
Registry title: Maternal Grandmothers in the Born in Guangzhou Cohort Study
Key facts
- Where
- Guangzhou, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 36 and 100 years old?
Source: NCT03633162, who can take part
Where in China
- Guangzhou Women and Children's medical centerGuangzhou, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Guangzhou Women and Children's Medical Center
- Trial code
- NCT03633162
- Record updated
- 16 September 2026
- Original description
The MGBIG is a study exploring cross-generational effects in 5000 women and their children and grandchildren located in Guangzhou, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology and on explaining the cause of the disease from the perspective of "grandmother-mother-child" heredity. Data are collected regarding environmental exposures, lifestyle, and social support on grandmother from birth to old age. Biological samples including blood and tissue samples are collected.Read full original descriptionShow less
Maternal Grandmothers in the Born in Guangzhou Cohort Study
The MGBIG is a study exploring cross-generational effects in 5000 women and their children and grandchildren located in Guangzhou, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology and on explaining the cause of the disease from the perspective of "grandmother-mother-child" heredity. Data are collected regarding environmental exposures, lifestyle, and social support on grandmother from birth to old age. Biological samples including blood and tissue samples are collected.
Inclusion: Maternal Grandmother' grandchildren delivered in Guangzhou Women and Children's Medical Center; Baseline information of maternal grandmother's daughter during pregnancy available.
Exclusion: Intelligent obstacle, intellectual disabilities or gawkish condition; Significant cardiovascular abnormalities.