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Intracameral Versus Intravitreal Bevacizumab Injection in NVG: RCT

Key facts

Where
Hat Yai, ThailandSee the site

Where in Thailand

  • Glaucoma unit , Department of Ophthalmology Faculty of Medicine Prince of Songkla UniversityHat Yai, ThailandTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Prince of Songkla University
Trial code
NCT03648814
Record updated
21 August 2025
Original description
To prospect studying the efficacy and safety of treating NVG with the intracameral versus the intravitreal injection of Bevacizumab.Read full original descriptionShow less

Efficacy and Safety of Intracameral Versus Intravitreal Bevacizumab Injection as an Adjunctive Therapy Before Trabeculectomy With Mitomycin-C in Neovascular Glaucoma: A Prospective Randomized Trial

To prospect studying the efficacy and safety of treating NVG with the intracameral versus the intravitreal injection of Bevacizumab.

Inclusion: Diagnosis of neovascular glaucoma; The patients having IOP > 21 mmHg, having the indication for trabeculectomy; The patients' age of at least 18-year-old; The patients having visual potential at least hand motion; Present of NVI or NVA; Willing and able to provide informed consent to participate in the study; Able to understand the purpose of the study, his/her role, and is available to return to the clinic/hospital for all required follow-up visits.

Exclusion: History of bevacizumab or fluorescence dye allergy; Active infectious ocular disease including endophthalmitis and corneal ulcer; History of systemic disease including ischemic heart disease, cerebrovascular disease, end-stage renal disease, liver failure, uncontrolled hypertension; Cannot obtain endothelial cell count; One eye patient; Patients having severe corneal edema or total hyphema obscure NVI or NVA view; Has or planning to be pregnant or breastfeeding.

ClinicalTrials.gov NCT03648814

Under construction, not live – Intracameral Versus Intravitreal Bevacizumab Injection in NVG: RCT (NCT03648814) – Frontlight Research