Studying how type 1 diabetes develops through genes and the immune system
Collects blood and health history from people to study how type 1 diabetes develops.
Plain-language title generated from the registry record
Registry title: Genetics Of Autoimmunity In Type I Diabetes
Key facts
- Where
- Milwaukee, United StatesSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for families where at least one close relative has type 1 diabetes, and also people with no family history of it or other autoimmune conditions as controls.
- Age
- 2 years and older.
- Sex
- All sexes can join.
- Disease stage
- Families: the person with type 1 diabetes was diagnosed before the age of 39.
Main reasons for not taking part
- Families with no history of type 1 diabetes
- Families with diabetes that is not type 1 (LADA, MODY, type 2 etc.)
- Controls with a personal or family history of autoimmune disease
Read by machine on 9 November 2026.
Where in United States
- Medical College of WisconsinMilwaukee, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Medical College of Wisconsin
- Trial code
- NCT03648918
- Record updated
- 16 March 2026
- Original description
The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 diabetes. Scientists think that a person's own immune system, directed by genetic and environmental factors play a major role in its development. Participation involves a blood draw, a brief medical history questionnaire and measurements of height and weight. Some participants will be asked to return for annual follow-up visits for 10 years.Read full original descriptionShow less
Genetics Of Autoimmunity In Type I Diabetes
The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 diabetes. Scientists think that a person's own immune system, directed by genetic and environmental factors play a major role in its development. Participation involves a blood draw, a brief medical history questionnaire and measurements of height and weight. Some participants will be asked to return for annual follow-up visits for 10 years.
Inclusion: Families where at least one first-degree family member has type 1 diabetes; The diabetic proband in the family was diagnosed before the age of 39; Family members must be at least 2 years old to participate; No family history of type 1 diabetes or other autoimmune conditions; Age 2 or older.
Exclusion: Families with no history of type 1 diabetes; Families with a history of diabetes that is not type 1 (LADA, MODY, type 2 etc.); Personal or family history of autoimmune disease.