Handgrip squeezing exercise and blood pressure in people with peripheral artery disease
Tests handgrip exercise on blood pressure in peripheral artery disease.
Key facts
- Who runs it
- University of Nove de Julho
- Where
- Brazil2 sites in 1 countryChoose a country to see its sites
- Trial code
- Registry title
- Handgrip Training in Patients With Peripheral Artery Disease
- Status
- Recruiting
- People taking part
- 30 people, planned
- Started
- 1 Aug 2018
- Expected to end
- 30 Dec 2027
- Type of study
- Interventional, 2 groups
- Treatments tested
- Isometric handgrip training
- Control Group
- Record updated
- 1 May 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women after menopause who have peripheral artery disease, which means narrowed leg arteries. It tests 12 weeks of handgrip squeezing exercise and its effect on blood pressure.
- Age
- 45 years and older
- Sex
- Women after menopause (the criteria ask for post-menopausal women)
- Disease stage
- Peripheral artery disease with an ankle-brachial index below 0.90. Blood pressure must be lower than 160mmHg systolic (top number) and 105mmHg diastolic (bottom number). No amputation of any limb.
- Earlier treatment
- Must not be taking hormone replacement therapy.
- Biomarker or test result
- Ankle-brachial index <0.90 (a test comparing blood pressure at the ankle and the arm).
Main reasons for not taking part
- Severe obesity (body mass index of 35kg/m2 or more)
- Amputation of a limb
- Changing medicines before the end of the training period
- Health problems that make physical activity impossible
- Taking hormone replacement therapy
The registry criteria, word for word
Show all 6 criteriaShow less
Who can take part
- Women in post-menopause phase without hormone replacement therapy
- Ankle-brachial index <0.90
- Not severe obese (≥ 35kg/m2)
- Not present amputation in the limbs
- Have blood pressure levels lower than 160mmHg for systolic and 105mmHg for diastolic
Who cannot take part
- patients will only be excluded if they make any medication changes before completing the intervention period or present any health problems that prevent physical activity
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The aim of this study is to analyze the effects of isometric handgrip training (IHT) on blood pressure of hypertensive patients with peripheral arterial disease. Will be recruited 30 patients which will be randomized into 2 groups (15 per group), IHT and control group (CG). IHT group will training isometric contraction for 12 weeks. In CG patients will be encouraged to increase the level of physical activity. In the pre and post-intervention cardiovascular measures will be obtained.
The 2 groups in the trial
- Isometric Handgrip TrainingTreatment being tested
Experimental group will perform home-based bilaterall handgrip exercise and will be recommended to increase daily physical activity levels.
- Control groupOther group
Control gorup will be recommended to increase daily physical activity level
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Effects of 12 Weeks of Isometric Handgrip Training in Blood Pressure in Patients With Peripheral Artery Disease
- Plain-language title
- Handgrip squeezing exercise and blood pressure in people with peripheral artery diseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Record updated
- 1 May 2026