Studies how the body's daily clock relates to blood metabolism markers
Observes whether body clock rhythms are linked to metabolism markers in young adults.
Plain-language title generated from the registry record
Registry title: The Biological Rhythm of Human Metabolite
Key facts
- Where
- Jinan, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 30 years old?
Source: NCT03669809, who can take part
Where in China
- Shandong Provincial HospitalJinan, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shandong Provincial Hospital
- Trial code
- NCT03669809
- Record updated
- 11 May 2022
- Original description
The circadian regulation in mammals have been known for a long time. A special group of clock genes, organized in feedback loops, are responsible for the circadian regulation in both the SCN and peripheral organs. The central clock is mainly entrained by the light-dark cycle, while the peripheral ones in organs such as liver and intestine, are more influenced by the feeding-fasting cycles. The coordination of central and peripheral clocks is thought to be essential in the maintenance of physiological homeostasis.This study aim to investigate the association between biological rhythm and metabolism.Read full original descriptionShow less
Association Between Serum Metabolism Markers and Biological Rhythm
The circadian regulation in mammals have been known for a long time. A special group of clock genes, organized in feedback loops, are responsible for the circadian regulation in both the SCN and peripheral organs. The central clock is mainly entrained by the light-dark cycle, while the peripheral ones in organs such as liver and intestine, are more influenced by the feeding-fasting cycles. The coordination of central and peripheral clocks is thought to be essential in the maintenance of physiological homeostasis.This study aim to investigate the association between biological rhythm and metabolism.
Inclusion: Male or female；; Aged of 18 to 30 years old.
Exclusion: Receiving psychotropic or hormonal medications including hormonal contraception and hormone therapies; Taking lipid-lowering agents or hypoglycemic agents and other drugs that known to influence cardiovascular health; Presence of pituitary/hypothalamic disorders, polycystic ovarian syndrome， thyroid disorders, hypertension, malignant tumor, cardiac insufficiency，hepatic or renal insufficiency, gastrointestinal disorders and acute infection; Pregnancy or lactation women; Obviously poor compliance.