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Long-term study of memory and aging with blood and spinal fluid samples

Studies blood and spinal fluid tests in adults with memory problems and healthy adults.

Plain-language title generated from the registry record
Registry title: DC Longitudinal Study on Aging and Specimen Bank

Key facts

Where
Washington D.C., United StatesSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 45 and older, with or without memory problems, to give blood or spinal fluid samples and take memory and lifestyle tests over time.

Age
45 years and older. People aged 45-50 must have a first degree relative with a neurodegenerative disease.
Sex
All sexes can join.

Main reasons for not taking part

  • People under 45 years of age cannot join.

Read by machine on 9 November 2026.

Where in United States

  • Georgetown University Memory Disorders ProgramWashington D.C., United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Georgetown University
Trial code
NCT03702907
Record updated
24 October 2019
Original description
The Georgetown University Memory Disorders Program, part of the Department of Neurology, is conducting pilot studies of the feasibility of various diagnostic tests for Alzheimer's disease, mild cognitive impairment and other neurodegenerative diseases. Further, this study is assessing longitudinal changes in biological, lifestyle, and cognitive assessment collection.Read full original descriptionShow less

DC Longitudinal Study on Aging and Specimen Bank

The Georgetown University Memory Disorders Program, part of the Department of Neurology, is conducting pilot studies of the feasibility of various diagnostic tests for Alzheimer's disease, mild cognitive impairment and other neurodegenerative diseases. Further, this study is assessing longitudinal changes in biological, lifestyle, and cognitive assessment collection.

The primary goal of this study is to examine the feasibility of biochemical assays, genetic testing, and cognitive and lifestyle assessments in the ante-mortem diagnosis of Alzheimer's disease, mild cognitive impairment and other neurodegenerative diseases. This research involves genetic and cognitive status testing but the findings will not be shared with research subjects. This will be accomplished ex vivo using blood, and/or cerebrospinal fluid (CSF) specimens from patients with a diagnosis of probable Alzheimer's disease, mild cognitive impairment, or other neurodegenerative diseases and from normal controls.

Inclusion: Age 45 and older; Subjects within the age range of 45-50 years old must have a first degree relative with a neurodegenerative disease.

Exclusion: Individuals under 45 years of age.

ClinicalTrials.gov NCT03702907